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Clinical and Socio-Demographic Variables Associated with the Diagnosis of Long COVID Syndrome in Youth: A Population-Based Study

Author

Listed:
  • Eugene Merzon

    (Leumit Health Services, Tel-Aviv 6473817, Israel
    Adelson School of Medicine, Ariel University, Ariel 4076414, Israel)

  • Margaret Weiss

    (Cambridge Health Alliance, Cambridge, MA 02139, USA)

  • Beth Krone

    (Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA)

  • Shira Cohen

    (ADHD Unit, Geha Mental Health Center, Petah Tikva 49100, Israel)

  • Gili Ilani

    (Department of Psychiatry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel)

  • Shlomo Vinker

    (Leumit Health Services, Tel-Aviv 6473817, Israel
    Department of Family Medicine, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel)

  • Avivit Cohen-Golan

    (Leumit Health Services, Tel-Aviv 6473817, Israel
    Department of Family Medicine, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel)

  • Ilan Green

    (Leumit Health Services, Tel-Aviv 6473817, Israel
    Department of Family Medicine, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel)

  • Ariel Israel

    (Leumit Health Services, Tel-Aviv 6473817, Israel)

  • Tzipporah Schneider

    (Clalit Health Services, Bnei Brak 5111501, Israel)

  • Shai Ashkenazi

    (Adelson School of Medicine, Ariel University, Ariel 4076414, Israel)

  • Abraham Weizman

    (ADHD Unit, Geha Mental Health Center, Petah Tikva 49100, Israel
    Department of Psychiatry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel)

  • Iris Manor

    (ADHD Unit, Geha Mental Health Center, Petah Tikva 49100, Israel
    Department of Psychiatry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel)

Abstract

This study examines the demographic, clinical and socioeconomic factors associated with diagnosis of long COVID syndrome (LCS). Data of 20,601 COVID-19-positive children aged 5 to 18 years were collected between 2020 and 2021 in an Israeli database. Logistic regression analysis was used to evaluate the adjusted odds ratio for the characteristics of the COVID-19 infection and pre-COVID-19 morbidities. Children with LCS were significantly more likely to have been severely symptomatic, required hospitalization, and experienced recurrent acute infection within 180 days. In addition, children with LCS were significantly more likely to have had ADHD, chronic urticaria, and allergic rhinitis. Diagnosis of LCS is significantly associated with pre-COVID-19 ADHD diagnosis, suggesting clinicians treating ADHD children who become infected with COVID-19 remain vigilant for the possibility of LCS. Although the risk of severe COVID-19 infection and LCS in children is low, further research on possible morbidity related to LCS in children is needed.

Suggested Citation

  • Eugene Merzon & Margaret Weiss & Beth Krone & Shira Cohen & Gili Ilani & Shlomo Vinker & Avivit Cohen-Golan & Ilan Green & Ariel Israel & Tzipporah Schneider & Shai Ashkenazi & Abraham Weizman & Iris , 2022. "Clinical and Socio-Demographic Variables Associated with the Diagnosis of Long COVID Syndrome in Youth: A Population-Based Study," IJERPH, MDPI, vol. 19(10), pages 1-11, May.
    • Handle: RePEc:gam:jijerp:v:19:y:2022:i:10:p:5993-:d:815923
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    References listed on IDEAS

    as
    1. Dian-Jeng Li & Yi-Lung Chen & Ray C. Hsiao & Hsiu-Lin Chen & Cheng-Fang Yen, 2021. "Risk of Respiratory Infectious Diseases and the Role of Methylphenidate in Children with Attention-Deficit/Hyperactivity Disorder: A Population-Based Cohort Study," IJERPH, MDPI, vol. 18(11), pages 1-9, May.
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      Keywords

      long COVID; ADHD; COVID-19; morbidity;
      All these keywords.

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