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Analyses of the Association between Thyroid Cancer and Osteoporosis/Fracture Histories: A Cross-Sectional Study Using KoGES HEXA Data

Author

Listed:
  • Young-Ju Jin

    (Department of Otorhinolaryngology-Head and Neck Surgery, Wonkwang University Hospital, Wonkwang University College of Medicine, Iksan 54538, Korea)

  • Chang-Myeon Song

    (Department of Otolaryngology-Head and Neck Surgery, Hanyang University College of Medicine, Seoul 04763, Korea)

  • Bum-Jung Park

    (Department of Otorhinolaryngology-Head and Neck Surgery, Hallym University College of Medicine, Anyang 14103, Korea)

  • Hyo-Geun Choi

    (Department of Otorhinolaryngology-Head and Neck Surgery, Hallym University College of Medicine, Anyang 14103, Korea
    Hallym Data Science Laboratory, Hallym University College of Medicine, Anyang 14103, Korea)

Abstract

(1) Background: The purpose of this study was to determine the association among thyroid cancer, osteoporosis and fracture history. (2) Methods: The data collected from 2004 through 2016 for the Korean Genome and Epidemiology Study were retrieved. For a total of 1349 participants with thyroid cancer and 163,629 control participants, the odds ratios (ORs) with 95% confidence intervals (CIs) of osteoporosis and fracture history were evaluated using a logistic regression model. (3) Results: The adjusted ORs of osteoporosis comparing thyroid cancer with the control group were 1.41 (95% CI = 1.18–1.70, p < 0.001) for all participants and 1.43 (95% CI = 1.19–1.71, p < 0.001) for women. The adjusted ORs of fracture history comparing these two groups were not significantly associated within the entire group of participants, men only or women only. (4) Conclusions: The adjusted OR of osteoporosis was significantly higher than 1, comparing thyroid cancer with the control group, especially in women. The adjusted OR of fractures was not significantly higher than 1, comparing the thyroid cancer group with the control group.

Suggested Citation

  • Young-Ju Jin & Chang-Myeon Song & Bum-Jung Park & Hyo-Geun Choi, 2021. "Analyses of the Association between Thyroid Cancer and Osteoporosis/Fracture Histories: A Cross-Sectional Study Using KoGES HEXA Data," IJERPH, MDPI, vol. 18(9), pages 1-8, April.
  • Handle: RePEc:gam:jijerp:v:18:y:2021:i:9:p:4732-:d:545873
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