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Comparison of Bone Tissue Trace Element Content in the Different Radiological Stages of Hip Osteoarthritis

Author

Listed:
  • Mikołaj Dąbrowski

    (Adult Spine Orthopaedics Department, Poznan University of Medical Sciences, 61-545 Poznan, Poland)

  • Anetta Zioła-Frankowska

    (Department of Analytical Chemistry, Faculty of Chemistry, Adam Mickiewicz University in Poznan, 61-614 Poznan, Poland)

  • Marcin Frankowski

    (Department of Analytical and Environmental Chemistry, Faculty of Chemistry, Adam Mickiewicz University in Poznan, 61-614 Poznan, Poland)

  • Jacek Kaczmarczyk

    (Poznan LAB, Institute of Practical Medicine, 62-081 Przezmierowo, Poland)

  • Łukasz Kubaszewski

    (Adult Spine Orthopaedics Department, Poznan University of Medical Sciences, 61-545 Poznan, Poland)

Abstract

Bone metabolism and the trace element content associated with it change at each stage of degenerative disease. The aim of this study was to find out about the role of the analyzed elements in different stages of hip osteoarthritis. Elements associated with oxidative and enzymatic processes were analyzed depending on the changes in the radiological images of the hip joint. Element content analysis was performed by the inductively coupled plasma mass spectrometry analytical technique. The femoral head in severely osteoarthritic hips (KL3–4) compared to mild grade osteoarthritis (KL2) had a greater content of Cu (median 1.04 vs. 0.04), Sr (median 38.71 vs. 29.59), and Zn (median 75.12 vs. 63.21). There were no significant differences in the content of Mo, Cr, and Fe in the femoral head and neck between the groups. The Cu/Fe correlation was negative in the KL2 group (−0.47) and positive in the KL3–4 groups (0.45). Changes in the content and correlation of trace elements in the hip joint explain the changes in metabolism dependent on the severity of degenerative changes.

Suggested Citation

  • Mikołaj Dąbrowski & Anetta Zioła-Frankowska & Marcin Frankowski & Jacek Kaczmarczyk & Łukasz Kubaszewski, 2021. "Comparison of Bone Tissue Trace Element Content in the Different Radiological Stages of Hip Osteoarthritis," IJERPH, MDPI, vol. 18(6), pages 1-9, March.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:6:p:3260-:d:521624
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    References listed on IDEAS

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    1. Virginia Byers Kraus, 2014. "The zinc link," Nature, Nature, vol. 507(7493), pages 441-442, March.
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    Cited by:

    1. Rafał Staszkiewicz & Kamil Bryś & Dorian Gładysz & Marcin Gralewski & Michał Garczarek & Marcin Gadzieliński & Jerzy Wieczorek & Wiesław Marcol & Aleksander Ostenda & Beniamin Oskar Grabarek, 2022. "Changes in Elements and Relationships among Elements in Intervertebral Disc Degeneration," IJERPH, MDPI, vol. 19(15), pages 1-18, July.

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