IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v18y2021i5p2246-d505127.html
   My bibliography  Save this article

Preterm Deliveries in Women with Uterine Myomas: The Japan Environment and Children’s Study

Author

Listed:
  • Tsuyoshi Murata

    (Fukushima Regional Center for the Japan Environment and Children’s Study, 1 Hikarigaoka, Fukushima 960-1295, Japan
    Department of Obstetrics and Gynecology, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima 960-1295, Japan)

  • Hyo Kyozuka

    (Fukushima Regional Center for the Japan Environment and Children’s Study, 1 Hikarigaoka, Fukushima 960-1295, Japan
    Department of Obstetrics and Gynecology, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima 960-1295, Japan)

  • Yuta Endo

    (Fukushima Regional Center for the Japan Environment and Children’s Study, 1 Hikarigaoka, Fukushima 960-1295, Japan
    Department of Obstetrics and Gynecology, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima 960-1295, Japan)

  • Toma Fukuda

    (Fukushima Regional Center for the Japan Environment and Children’s Study, 1 Hikarigaoka, Fukushima 960-1295, Japan
    Department of Obstetrics and Gynecology, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima 960-1295, Japan)

  • Shun Yasuda

    (Fukushima Regional Center for the Japan Environment and Children’s Study, 1 Hikarigaoka, Fukushima 960-1295, Japan
    Department of Obstetrics and Gynecology, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima 960-1295, Japan)

  • Akiko Yamaguchi

    (Fukushima Regional Center for the Japan Environment and Children’s Study, 1 Hikarigaoka, Fukushima 960-1295, Japan
    Department of Obstetrics and Gynecology, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima 960-1295, Japan)

  • Akiko Sato

    (Fukushima Regional Center for the Japan Environment and Children’s Study, 1 Hikarigaoka, Fukushima 960-1295, Japan)

  • Yuka Ogata

    (Fukushima Regional Center for the Japan Environment and Children’s Study, 1 Hikarigaoka, Fukushima 960-1295, Japan)

  • Kosei Shinoki

    (Fukushima Regional Center for the Japan Environment and Children’s Study, 1 Hikarigaoka, Fukushima 960-1295, Japan)

  • Mitsuaki Hosoya

    (Fukushima Regional Center for the Japan Environment and Children’s Study, 1 Hikarigaoka, Fukushima 960-1295, Japan
    Department of Pediatrics, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima 960-1295, Japan)

  • Seiji Yasumura

    (Fukushima Regional Center for the Japan Environment and Children’s Study, 1 Hikarigaoka, Fukushima 960-1295, Japan
    Department of Public Health, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima 960-1295, Japan)

  • Koichi Hashimoto

    (Fukushima Regional Center for the Japan Environment and Children’s Study, 1 Hikarigaoka, Fukushima 960-1295, Japan
    Department of Pediatrics, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima 960-1295, Japan)

  • Hidekazu Nishigori

    (Fukushima Regional Center for the Japan Environment and Children’s Study, 1 Hikarigaoka, Fukushima 960-1295, Japan
    Fukushima Medical Center for Children and Women, Fukushima Medical University, 1 Hikarigaoka, Fukushima 960-1295, Japan)

  • Keiya Fujimori

    (Fukushima Regional Center for the Japan Environment and Children’s Study, 1 Hikarigaoka, Fukushima 960-1295, Japan
    Department of Obstetrics and Gynecology, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima 960-1295, Japan)

  • The Japan Environment Children’s Study (JECS) Group

    (Membership of the Japan Environment and Children’s Study (JECS) Group is provided in the Acknowledgments)

Abstract

This study aimed to clarify the association between uterine myomas and preterm birth (PTB), preterm premature rupture of membranes (pPROM), and intrauterine infection (II). The study was based on data from the Japan Environment and Children’s Study, a nationwide birth-cohort study. Data of 86,370 women with singleton births after 22 weeks of gestation (with uterine myomas, n = 5354) were retrospectively analyzed. Using logistic regression, adjusted odds ratios (aORs) for PTB, pPROM, and II were calculated considering women without uterine myomas as the reference. Additionally, the effects of II on the incidence of PTB and pPROM were evaluated. In women with uterine myomas, the aORs for PTB before 37 and 34 weeks, pPROM, and II were 1.37 (95% confidence interval, 1.22–1.54), 1.61 (1.27–2.05), 1.65 (1.33–2.04), and 1.05 (0.75–1.46), respectively. The aORs for PTB and pPROM in women with II and uterine myomas were not significantly increased. Uterine myomas during pregnancy were associated with an increased incidence of PTB and pPROM. However, II in women with uterine myomas was not associated with an increased incidence of PTB or pPROM. These findings suggest a potential risk of occult PTB in pregnant women with uterine myomas.

Suggested Citation

  • Tsuyoshi Murata & Hyo Kyozuka & Yuta Endo & Toma Fukuda & Shun Yasuda & Akiko Yamaguchi & Akiko Sato & Yuka Ogata & Kosei Shinoki & Mitsuaki Hosoya & Seiji Yasumura & Koichi Hashimoto & Hidekazu Nishi, 2021. "Preterm Deliveries in Women with Uterine Myomas: The Japan Environment and Children’s Study," IJERPH, MDPI, vol. 18(5), pages 1-9, February.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:5:p:2246-:d:505127
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/18/5/2246/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/18/5/2246/
    Download Restriction: no
    ---><---

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:18:y:2021:i:5:p:2246-:d:505127. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.