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A Clinical-Epidemiological and Geospatial Study of Tuberculosis in a Neglected Area in the Amazonian Region Highlights the Urgent Need for Control Measures

Author

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  • Cristal Ribeiro Mesquita

    (Programa de Pós-Graduação em Biologia Parasitária na Amazônia, Universidade do Estado do Pará e Instituto Evandro Chagas, Tv. Perebebui, 2623, Belem 66087-662, Brazil
    Programa de Pós-Graduação em Epidemiologia e Vigilância em Saúde, Instituto Evandro Chagas, BR 316, km 7, Ananindeua 67000-000, Brazil
    Seção de Bacteriologia e Micologia, Instituto Evandro Chagas, BR 316, km 7, Ananindeua 67000-000, Brazil)

  • Emilyn Costa Conceição

    (Programa de Pós-Graduação em Pesquisa Clínica em Doenças Infecciosas do Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Av. Brasil, 4365, Rio de Janeiro 21040-900, Brazil)

  • Lúcia Helena Martins Tavares Monteiro

    (Secretaria de Saúde do Estado do Pará-SESPA, Av. João Paulo II, 602, Belem 66087-048, Brazil)

  • Odinea Maria da Silva

    (Secretaria de Saúde do Estado do Pará-SESPA, Av. João Paulo II, 602, Belem 66087-048, Brazil)

  • Luana Nepomuceno Gondim Costa Lima

    (Programa de Pós-Graduação em Biologia Parasitária na Amazônia, Universidade do Estado do Pará e Instituto Evandro Chagas, Tv. Perebebui, 2623, Belem 66087-662, Brazil
    Programa de Pós-Graduação em Epidemiologia e Vigilância em Saúde, Instituto Evandro Chagas, BR 316, km 7, Ananindeua 67000-000, Brazil
    Seção de Bacteriologia e Micologia, Instituto Evandro Chagas, BR 316, km 7, Ananindeua 67000-000, Brazil)

  • Rafael Aleixo Coelho de Oliveira

    (Programa de Pós-Graduação em Saúde, Ambiente e Sociedade, Universidade Federal do Pará, Rua Augusto Corrêa, Belem 66075-110, Brazil)

  • Artemir Coelho de Brito

    (Coordenação Geral de Vigilância das Doenças de Transmissão Respiratória de Condições Crônicas, Av. Brasil, 4365, Rio de Janeiro 21040-900, Brazil)

  • Ricardo José de Paula Souza e Guimarães

    (Programa de Pós-Graduação em Epidemiologia e Vigilância em Saúde, Instituto Evandro Chagas, BR 316, km 7, Ananindeua 67000-000, Brazil)

  • Karla Valéria Batista Lima

    (Programa de Pós-Graduação em Biologia Parasitária na Amazônia, Universidade do Estado do Pará e Instituto Evandro Chagas, Tv. Perebebui, 2623, Belem 66087-662, Brazil
    Seção de Bacteriologia e Micologia, Instituto Evandro Chagas, BR 316, km 7, Ananindeua 67000-000, Brazil)

Abstract

Tuberculosis (TB) is an infectious communicable disease, which despite global efforts, still needs special attention in regions with difficult access. This study aims to describe the spatial and epidemiological trends of TB incidences from 2013 to 2018 in Marajó Island, the Amazonian region, Pará, Brazil. We have obtained secondary data from the Brazilian TB databases and performed geospatial and statistical analyses on the data for new TB cases, relapses, and re-admissions. From 2013 to 2018, 749 new cases were reported, in which the diagnostics (culture) was not performed for 652 (87.2%) patient samples, the drug resistance test (DST) was performed for nine (1.2%) samples, and one (0.13%) was multidrug-resistant TB (MDR-TB). The rapid molecular testing (RMT) was performed on 40 (5.3%) patient samples, with results indicating that eight (20%) were susceptible to rifampicin and two (5%) were rifampicin resistant. Overall, the cure rate was 449 (66.7%), while relapses and re-admissions were 41 and 44, respectively. On the geospatial distribution, the municipality of Soure stands out with a high number of incidences, relapses, and re-admissions. Spatially, the eight MDR cases were randomly distributed. Our data highlight the urgent need for TB control measures in this region, by introducing the Xpert-Ultra ® MTB/RIF (Cepheid, Sunnyvale, CA, USA) and Ogawa-Kudoh.

Suggested Citation

  • Cristal Ribeiro Mesquita & Emilyn Costa Conceição & Lúcia Helena Martins Tavares Monteiro & Odinea Maria da Silva & Luana Nepomuceno Gondim Costa Lima & Rafael Aleixo Coelho de Oliveira & Artemir Coel, 2021. "A Clinical-Epidemiological and Geospatial Study of Tuberculosis in a Neglected Area in the Amazonian Region Highlights the Urgent Need for Control Measures," IJERPH, MDPI, vol. 18(3), pages 1-15, February.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:3:p:1335-:d:491760
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