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Incidence of Anxiety in Latest Life and Risk Factors. Results of the AgeCoDe/AgeQualiDe Study

Author

Listed:
  • Franziska Dinah Welzel

    (Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, 04103 Leipzig, Germany)

  • Melanie Luppa

    (Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, 04103 Leipzig, Germany)

  • Alexander Pabst

    (Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, 04103 Leipzig, Germany)

  • Michael Pentzek

    (Institute of General Practice, Medical Faculty, Heinrich-Heine-University Düsseldorf, 40225 Düsseldorf, Germany)

  • Angela Fuchs

    (Institute of General Practice, Medical Faculty, Heinrich-Heine-University Düsseldorf, 40225 Düsseldorf, Germany)

  • Dagmar Weeg

    (Department of Psychiatry, Technical University of Munich, 81675 Munich, Germany)

  • Horst Bickel

    (Department of Psychiatry, Technical University of Munich, 81675 Munich, Germany)

  • Siegfried Weyerer

    (Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany)

  • Jochen Werle

    (Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, 68159 Mannheim, Germany)

  • Birgitt Wiese

    (Institute for General Practice, Hannover Medical School, 30625 Hannover, Germany)

  • Anke Oey

    (Institute for General Practice, Hannover Medical School, 30625 Hannover, Germany)

  • Christian Brettschneider

    (Department of Health Economics and Health Services Research, University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany)

  • Hans-Helmut König

    (Department of Health Economics and Health Services Research, University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany)

  • Kathrin Heser

    (Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, 53127 Bonn, Germany)

  • Hendrik van den Bussche

    (Department of Primary Medical Care, Center for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany)

  • Marion Eisele

    (Department of Primary Medical Care, Center for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany)

  • Wolfgang Maier

    (Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, 53127 Bonn, Germany)

  • Martin Scherer

    (Department of Primary Medical Care, Center for Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany)

  • Michael Wagner

    (Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, 53127 Bonn, Germany
    German Center for Neurodegenerative Diseases (DZNE), 53127 Bonn, Germany
    Shared last authorship.)

  • Steffi G. Riedel-Heller

    (Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, 04103 Leipzig, Germany
    Shared last authorship.)

Abstract

Research on anxiety in oldest-old individuals is scarce. Specifically, incidence studies based on large community samples are lacking. The objective of this study is to assess age- and gender-specific incidence rates in a large sample of oldest-old individuals and to identify potential risk factors. The study included data from N = 702 adults aged 81 to 97 years. Anxiety symptoms were identified using the short form of the Geriatric Anxiety Inventory (GAI-SF). Associations of potential risk factors with anxiety incidence were analyzed using Cox proportional hazard models. Out of the N = 702 older adults, N = 77 individuals developed anxiety symptoms during the follow-up period. The incidence rate was 51.3 (95% CI: 41.2–64.1) per 1000 person-years in the overall sample, compared to 58.5 (95% CI: 43.2–72.4) in women and 37.3 (95% CI: 23.6–58.3) in men. Multivariable analysis showed an association of subjective memory complaints (HR: 2.03, 95% CI: 1.16–3.57) and depressive symptoms (HR: 3.20, 95% CI: 1.46–7.01) with incident anxiety in the follow-up. Incident anxiety is highly common in late life. Depressive symptoms and subjective memory complaints are major risk factors of new episodes. Incident anxiety appears to be a response to subjective memory complaints independent of depressive symptoms.

Suggested Citation

  • Franziska Dinah Welzel & Melanie Luppa & Alexander Pabst & Michael Pentzek & Angela Fuchs & Dagmar Weeg & Horst Bickel & Siegfried Weyerer & Jochen Werle & Birgitt Wiese & Anke Oey & Christian Brettsc, 2021. "Incidence of Anxiety in Latest Life and Risk Factors. Results of the AgeCoDe/AgeQualiDe Study," IJERPH, MDPI, vol. 18(23), pages 1-16, December.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:23:p:12786-:d:694832
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