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In-Hospital Mortality in Non-COVID-19-Related Diseases before and during the Pandemic: A Regional Retrospective Study

Author

Listed:
  • Nicola Bartolomeo

    (Department of Biomedical Sciences and Human Oncology, University of Bari Aldo Moro, 70124 Bari, Italy)

  • Massimo Giotta

    (Department of Biomedical Sciences and Human Oncology, University of Bari Aldo Moro, 70124 Bari, Italy)

  • Paolo Trerotoli

    (Department of Biomedical Sciences and Human Oncology, University of Bari Aldo Moro, 70124 Bari, Italy)

Abstract

Italy was one of the nations most affected by SARS-CoV-2. During the pandemic period, the national government approved some restrictions to reduce diffusion of the virus. We aimed to evaluate changes in in-hospital mortality and its possible relation with patient comorbidities and different restrictive public health measures adopted during the 2020 pandemic period. We analyzed the hospital discharge records of inpatients from public and private hospitals in Apulia (Southern Italy) from 1 January 2019 to 31 December 2020. The study period was divided into four phases according to administrative restriction. The possible association between in-hospital deaths, hospitalization period, and covariates such as age group, sex, Charlson comorbidity index (CCI) class, and length of hospitalization stay (LoS) class was evaluated using a multivariable logistic regression model. The risk of death was slightly higher in men than in women (OR 1.04, 95% CI: 1.01–1.07) and was lower for every age group below the >75 years age group. The risk of in-hospital death was lower for hospitalizations with a lower CCI score. In summary, our analysis shows a possible association between in-hospital mortality in non-COVID-19-related diseases and restrictive measures of public health. The risk of hospital death increased during the lockdown period.

Suggested Citation

  • Nicola Bartolomeo & Massimo Giotta & Paolo Trerotoli, 2021. "In-Hospital Mortality in Non-COVID-19-Related Diseases before and during the Pandemic: A Regional Retrospective Study," IJERPH, MDPI, vol. 18(20), pages 1-13, October.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:20:p:10886-:d:657988
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    Citations

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    Cited by:

    1. Nicola Bartolomeo & Massimo Giotta & Silvio Tafuri & Paolo Trerotoli, 2022. "Impact of Socioeconomic Deprivation on the Local Spread of COVID-19 Cases Mediated by the Effect of Seasons and Restrictive Public Health Measures: A Retrospective Observational Study in Apulia Region," IJERPH, MDPI, vol. 19(18), pages 1-16, September.
    2. Francesco Addabbo & Massimo Giotta & Antonia Mincuzzi & Aldo Sante Minerba & Rosa Prato & Francesca Fortunato & Nicola Bartolomeo & Paolo Trerotoli, 2023. "No Excess of Mortality from Lung Cancer during the COVID-19 Pandemic in an Area at Environmental Risk: Results of an Explorative Analysis," IJERPH, MDPI, vol. 20(8), pages 1-16, April.
    3. Małgorzata Kowalska & Ewa Niewiadomska, 2022. "Spatial Variability of COVID-19 Hospitalization in the Silesian Region, Poland," IJERPH, MDPI, vol. 19(15), pages 1-11, July.
    4. Massimo Giotta & Paolo Trerotoli & Vincenzo Ostilio Palmieri & Francesca Passerini & Piero Portincasa & Ilaria Dargenio & Jihad Mokhtari & Maria Teresa Montagna & Danila De Vito, 2022. "Application of a Decision Tree Model to Predict the Outcome of Non-Intensive Inpatients Hospitalized for COVID-19," IJERPH, MDPI, vol. 19(20), pages 1-12, October.

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