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A Health Technology Assessment in Maxillofacial Cancer Surgery by Using the Six Sigma Methodology

Author

Listed:
  • Carlo Ricciardi

    (Department of Electrical Engineering and Information Technology, University of Naples “Federico II”, 80125 Naples, Italy
    Bioengineering Unit, Institute of Care and Scientific Research Maugeri, 27100 Pavia, Italy)

  • Giovanni Dell’Aversana Orabona

    (Maxillofacial Surgery Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences, University Hospital of Naples “Federico II”, 80131 Napoli, Italy)

  • Ilaria Picone

    (Department of Advanced Biomedical Sciences, University Hospital of Naples “Federico II”, 80131 Naples, Italy)

  • Imma Latessa

    (Department of Public Health, University Hospital of Naples “Federico II”, 80131 Naples, Italy)

  • Antonella Fiorillo

    (Department of Advanced Biomedical Sciences, University Hospital of Naples “Federico II”, 80131 Naples, Italy)

  • Alfonso Sorrentino

    (Maxillofacial Surgery Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences, University Hospital of Naples “Federico II”, 80131 Napoli, Italy)

  • Maria Triassi

    (Department of Public Health, University Hospital of Naples “Federico II”, 80131 Naples, Italy
    Interdepartmental Center for Research in Healthcare Management and Innovation in Healthcare (CIRMIS), University of Naples “Federico II”, 80131 Naples, Italy)

  • Giovanni Improta

    (Department of Public Health, University Hospital of Naples “Federico II”, 80131 Naples, Italy
    Interdepartmental Center for Research in Healthcare Management and Innovation in Healthcare (CIRMIS), University of Naples “Federico II”, 80131 Naples, Italy)

Abstract

Squamous cell carcinoma represents the most common cancer affecting the oral cavity. At the University of Naples “Federico II”, two different antibiotic protocols were used in patients undergoing oral mucosa cancer surgery from 2006 to 2018. From 2011, there was a shift; the combination of Cefazolin plus Clindamycin as a postoperative prophylactic protocol was chosen. In this paper, a health technology assessment (HTA) is performed by using the Six Sigma and DMAIC (Define, Measure, Analyse, Improve, Control) cycle in order to compare the performance of the antibiotic protocols according to the length of hospital stay (LOS). The data (13 variables) of two groups were collected and analysed; overall, 136 patients were involved. The American Society of Anaesthesiologist score, use of lymphadenectomy or tracheotomy and the presence of infections influenced LOS significantly ( p -value < 0.05) in both groups. Then, the groups were compared: the overall difference between LOS of the groups was not statistically significant, but some insights were provided by comparing the LOS of the groups according to each variable. In conclusion, in light of the insights provided by this study regarding the comparison of two antibiotic protocols, the utilization of DMAIC cycle and Six Sigma tools to perform HTA studies could be considered in future research.

Suggested Citation

  • Carlo Ricciardi & Giovanni Dell’Aversana Orabona & Ilaria Picone & Imma Latessa & Antonella Fiorillo & Alfonso Sorrentino & Maria Triassi & Giovanni Improta, 2021. "A Health Technology Assessment in Maxillofacial Cancer Surgery by Using the Six Sigma Methodology," IJERPH, MDPI, vol. 18(18), pages 1-16, September.
    • Handle: RePEc:gam:jijerp:v:18:y:2021:i:18:p:9846-:d:638524
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    References listed on IDEAS

    as
    1. Giovanni Improta & Guido Guizzi & Carlo Ricciardi & Vincenzo Giordano & Alfonso Maria Ponsiglione & Giuseppe Converso & Maria Triassi, 2020. "Agile Six Sigma in Healthcare: Case Study at Santobono Pediatric Hospital," IJERPH, MDPI, vol. 17(3), pages 1-17, February.
    2. Giovanni Improta & Giuseppe Converso & Teresa Murino & Mosè Gallo & Antonietta Perrone & Maria Romano, 2019. "Analytic Hierarchy Process (AHP) in Dynamic Configuration as a Tool for Health Technology Assessment (HTA): The Case of Biosensing Optoelectronics in Oncology," International Journal of Information Technology & Decision Making (IJITDM), World Scientific Publishing Co. Pte. Ltd., vol. 18(05), pages 1533-1550, September.
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