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Mandibular Brown Tumor as a Result of Secondary Hyperparathyroidism: A Case Report with 5 Years Follow-Up and Review of the Literature

Author

Listed:
  • Veronika Shavlokhova

    (Department of Oral and Cranio-Maxillofacial Surgery, University Hospital Heidelberg, 69120 Heidelberg, Germany)

  • Benjamin Goeppert

    (Institute of Pathology, University Hospital Heidelberg, 69120 Heidelberg, Germany)

  • Matthias M. Gaida

    (Institute of Pathology, University Hospital Heidelberg, 69120 Heidelberg, Germany
    Institute of Pathology, University Medical Center Mainz, Johannes Gutenberg-Universität Mainz, 55131 Mainz, Germany)

  • Babak Saravi

    (Department of Orthopedics and Trauma Surgery, Medical Centre-Albert-Ludwigs-University of Freiburg, Faculty of Medicine, Albert-Ludwigs-University of Freiburg, 79106 Freiburg, Germany)

  • Frederic Weichel

    (Department of Oral and Cranio-Maxillofacial Surgery, University Hospital Heidelberg, 69120 Heidelberg, Germany)

  • Andreas Vollmer

    (Department of Oral and Cranio-Maxillofacial Surgery, University Hospital Heidelberg, 69120 Heidelberg, Germany)

  • Michael Vollmer

    (Department of Oral and Cranio-Maxillofacial Surgery, University Hospital Heidelberg, 69120 Heidelberg, Germany)

  • Christian Freudlsperger

    (Department of Oral and Cranio-Maxillofacial Surgery, University Hospital Heidelberg, 69120 Heidelberg, Germany)

  • Christian Mertens

    (Department of Oral and Cranio-Maxillofacial Surgery, University Hospital Heidelberg, 69120 Heidelberg, Germany)

  • Jürgen Hoffmann

    (Department of Oral and Cranio-Maxillofacial Surgery, University Hospital Heidelberg, 69120 Heidelberg, Germany)

Abstract

Background: Brown tumor is a rare skeletal manifestation of secondary hyperparathyroidism. Although diagnosis of the disease is increasingly seen in early stages due to improved screening techniques, some patients still present in a progressed disease stage. The treatment depends on tumor mass and varies from a conservative approach with supportive parathyroidectomy to extensive surgical resection with subsequent reconstruction. Case presentation: We report a case of extensive mandibular brown tumor in a patient with a history of systemic lupus erythematosus, chronic kidney disease, and secondary hyperparathyroidism. Following radical resection of the affected bone, reconstruction could be successfully performed using a free flap. Conclusions: There were no signs of recurrence during five years of close follow-up. Increased awareness and multidisciplinary follow-ups could allow early diagnosis and prevent the need for radical therapeutical approaches.

Suggested Citation

  • Veronika Shavlokhova & Benjamin Goeppert & Matthias M. Gaida & Babak Saravi & Frederic Weichel & Andreas Vollmer & Michael Vollmer & Christian Freudlsperger & Christian Mertens & Jürgen Hoffmann, 2021. "Mandibular Brown Tumor as a Result of Secondary Hyperparathyroidism: A Case Report with 5 Years Follow-Up and Review of the Literature," IJERPH, MDPI, vol. 18(14), pages 1-11, July.
  • Handle: RePEc:gam:jijerp:v:18:y:2021:i:14:p:7370-:d:591712
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