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Efficacy of Sea Salt-Based Mouthwash and Xylitol in Improving Oral Hygiene among Adolescent Population: A Pilot Study

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Listed:
  • Andrea Ballini

    (Department of Biosciences, Biotechnologies and Biopharmaceutics, Campus Universitario “Ernesto Quagliariello”, University of Bari Aldo Moro, 70125 Bari, Italy
    Department of Precision Medicine, University of Campania “Luigi Vanvitelli”, 80100 Naples, Italy
    Contributed equally to this work as co-first authors.)

  • Stefania Cantore

    (Department of Interdisciplinary Medicine, University of Bari Aldo Moro, 70124 Bari, Italy
    Contributed equally to this work as co-first authors.)

  • Luca Signorini

    (Dental School, Unicamillus University, 00131 Rome, Italy)

  • Rajiv Saini

    (Department of Interdisciplinary Medicine, University of Bari Aldo Moro, 70124 Bari, Italy)

  • Salvatore Scacco

    (Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, 70124 Bari, Italy)

  • Antonio Gnoni

    (Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, 70124 Bari, Italy)

  • Alessio Danilo Inchingolo

    (Department of Interdisciplinary Medicine, University of Bari Aldo Moro, 70124 Bari, Italy)

  • Danila De Vito

    (Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari Aldo Moro, 70124 Bari, Italy)

  • Luigi Santacroce

    (Department of Interdisciplinary Medicine, University of Bari Aldo Moro, 70124 Bari, Italy
    School of Technical Medical Sciences, “A. Xhuvani” University, 3001 Elbasan, Albania
    Contributed equally to this work as co-last authors.)

  • Francesco Inchingolo

    (Department of Interdisciplinary Medicine, University of Bari Aldo Moro, 70124 Bari, Italy
    Contributed equally to this work as co-last authors.)

  • Gianna Dipalma

    (Department of Interdisciplinary Medicine, University of Bari Aldo Moro, 70124 Bari, Italy
    Contributed equally to this work as co-last authors.)

Abstract

The scientific community has definitely demonstrated the importance of the use of mouthwash in daily oral hygiene. In our pilot study, we tested the effectiveness of a novel mouth rinse containing sea salt, xylitol, and lysozyme. Streptococcus mutans (S. mutans) growth, and plaque index in adolescent patients aged 14–17 years, were observed. The bacterial load was investigated by in vitro microbiological analysis; the plaque index was assessed through the O’Leary’s Plaque Control Record (PCR). The study has shown that the use of a sea salt-based mouthwash in daily oral hygiene reduces the bacterial levels of S. mutans ( p < 0.01) linked to the combined action of xylitol and lysozyme, together with the action of sea salt. Our preliminary data confirm and improve the main results reported in the scientific literature on the importance of the use of xylitol, lysozyme, and sea salt in oral health.

Suggested Citation

  • Andrea Ballini & Stefania Cantore & Luca Signorini & Rajiv Saini & Salvatore Scacco & Antonio Gnoni & Alessio Danilo Inchingolo & Danila De Vito & Luigi Santacroce & Francesco Inchingolo & Gianna Dipa, 2020. "Efficacy of Sea Salt-Based Mouthwash and Xylitol in Improving Oral Hygiene among Adolescent Population: A Pilot Study," IJERPH, MDPI, vol. 18(1), pages 1-10, December.
    • Handle: RePEc:gam:jijerp:v:18:y:2020:i:1:p:44-:d:467063
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    References listed on IDEAS

    as
    1. Małgorzata Staszczyk & Anna Jurczak & Marcin Magacz & Dorota Kościelniak & Iwona Gregorczyk-Maga & Małgorzata Jamka-Kasprzyk & Magdalena Kępisty & Iwona Kołodziej & Magdalena Kukurba-Setkowicz & Wirgi, 2020. "Effect of Polyols and Selected Dental Materials on the Ability to Create a Cariogenic Biofilm–On Children Caries-Associated Streptococcus Mutans Isolates," IJERPH, MDPI, vol. 17(10), pages 1-20, May.
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