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Maternal Health and Nutrition Status, Human Milk Composition, and Growth and Development of Infants and Children: A Prospective Japanese Human Milk Study Protocol

Author

Listed:
  • Keisuke Nojiri

    (Research and Development Department, Bean Stalk Snow Co., Ltd., Saitama 350-1165, Japan)

  • Shunjiro Kobayashi

    (Megmilk Snow Brand Co., Ltd., Tokyo 160-8575, Japan)

  • Satoshi Higurashi

    (Research and Development Department, Bean Stalk Snow Co., Ltd., Saitama 350-1165, Japan)

  • Tomoki Takahashi

    (Research and Development Department, Bean Stalk Snow Co., Ltd., Saitama 350-1165, Japan)

  • Yuta Tsujimori

    (Research and Development Department, Bean Stalk Snow Co., Ltd., Saitama 350-1165, Japan)

  • Hiroshi M. Ueno

    (Research and Development Department, Bean Stalk Snow Co., Ltd., Saitama 350-1165, Japan)

  • Shiomi Watanabe-Matsuhashi

    (Megmilk Snow Brand Co., Ltd., Tokyo 160-8575, Japan)

  • Yasuhiro Toba

    (Research and Development Department, Bean Stalk Snow Co., Ltd., Saitama 350-1165, Japan)

  • Junichi Yamamura

    (Megmilk Snow Brand Co., Ltd., Tokyo 160-8575, Japan)

  • Taku Nakano

    (Megmilk Snow Brand Co., Ltd., Tokyo 160-8575, Japan)

  • Kyoko Nomura

    (Department of Environmental Health Science and Public Health, Akita University Graduate School of Medicine, Akita 010-8543, Japan)

  • Toshiya Kobayashi

    (Research and Development Department, Bean Stalk Snow Co., Ltd., Saitama 350-1165, Japan)

Abstract

It is unknown whether maternal health and nutrition are related to human milk composition or growth and development of infants and children. Here, we describe a protocol for a prospective five-year cohort study to clarify (i) how maternal health and nutrition, socioeconomic factors, and lifestyles affect human milk composition, and (ii) whether these are associated with growth and development of infants and children. In our study, we recruited 1210 Japanese mothers with singleton pregnancies from 73 obstetrics clinics and hospitals across Japan, between 2014 and 2019. We will measure the following: health information regarding maternal-child dyads using a self-administered questionnaire, maternal nutrition during breastfeeding using a Brief self-administrated Diet History Questionnaire, the development of infants and children using the Kinder Infant Development Scale, and the stress related to child rearing using the Mother’s Child Care Stress Scale. Simultaneously, we will collect human milk every 2 months during the first year after birth to measure its composition and levels of macronutrients. This study will generate useful data to investigate whether health status, nutritional status, lifestyle, and socioeconomic factors affect human milk composition and the growth and development of infants and children.

Suggested Citation

  • Keisuke Nojiri & Shunjiro Kobayashi & Satoshi Higurashi & Tomoki Takahashi & Yuta Tsujimori & Hiroshi M. Ueno & Shiomi Watanabe-Matsuhashi & Yasuhiro Toba & Junichi Yamamura & Taku Nakano & Kyoko Nomu, 2020. "Maternal Health and Nutrition Status, Human Milk Composition, and Growth and Development of Infants and Children: A Prospective Japanese Human Milk Study Protocol," IJERPH, MDPI, vol. 17(6), pages 1-10, March.
  • Handle: RePEc:gam:jijerp:v:17:y:2020:i:6:p:1869-:d:332064
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    References listed on IDEAS

    as
    1. Aya Hisada & Jun Yoshinaga & Jie Zhang & Takahiko Katoh & Hiroaki Shiraishi & Kazuhisa Shimodaira & Takashi Okai & Nagako Ariki & Yoko Komine & Miyako Shirakawa & Yumiko Noda & Nobumasa Kato, 2017. "Maternal Exposure to Pyrethroid Insecticides during Pregnancy and Infant Development at 18 Months of Age," IJERPH, MDPI, vol. 14(1), pages 1-9, January.
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