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Use of Medications by Breastfeeding Women in the 2015 Pelotas (Brazil) Birth Cohort Study

Author

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  • Bárbara Heather Lutz

    (Department of Social Medicine, Faculty of Medicine, Federal University of Pelotas, Avenida Duque de Caxias, 250, Pelotas 96030-000, RS, Brazil
    Post-Graduate Program in Epidemiology, Federal University of Pelotas, Rua Marechal Deodoro, 1160, Pelotas 96020-220, RS, Brazil)

  • Diego Garcia Bassani

    (Centre for Global Child Health, Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada
    Department of Paediatrics, University of Toronto, 555 University Avenue, Toronto, ON M5G 1X8, Canada)

  • Vanessa Iribarrem Avena Miranda

    (Post-Graduate Program in Epidemiology, Federal University of Pelotas, Rua Marechal Deodoro, 1160, Pelotas 96020-220, RS, Brazil)

  • Marysabel Pinto Telis Silveira

    (Post-Graduate Program in Epidemiology, Federal University of Pelotas, Rua Marechal Deodoro, 1160, Pelotas 96020-220, RS, Brazil
    Department of Physiology and Pharmacology, Institute of Biology, Federal University of Pelotas, Travessa André Dreyfus, s/n, Campus Capão do Leão, Pelotas 96010-900, RS, Brazil)

  • Sotero Serrate Mengue

    (Post-Graduate Program in Epidemiology, Federal University of Porto Alegre, Av. Ipiranga, 2752, Sala 203, Porto Alegre 96020-000, RS, Brazil)

  • Tatiane da Silva Dal Pizzol

    (Post-Graduate Program in Epidemiology, Federal University of Porto Alegre, Av. Ipiranga, 2752, Sala 203, Porto Alegre 96020-000, RS, Brazil)

  • Mariângela Freitas da Silveira

    (Post-Graduate Program in Epidemiology, Federal University of Pelotas, Rua Marechal Deodoro, 1160, Pelotas 96020-220, RS, Brazil)

  • Andréa Dâmaso Bertoldi

    (Post-Graduate Program in Epidemiology, Federal University of Pelotas, Rua Marechal Deodoro, 1160, Pelotas 96020-220, RS, Brazil)

Abstract

Background: This study describes medication use by women up to 3 months postpartum and evaluates the association between medication use by women who were still breastfeeding at 3 months postpartum and weaning at 6 and 12 months. Methods: Population-based cohort, including women who breastfed ( n = 3988). Medications were classified according to Hale’s lactation risk categories and Brazilian Ministry of Health criteria. Duration of breastfeeding was analysed using Cox regression models and Kaplan-Meier curves, including only women who were still breastfeeding at three months postpartum. Results: Medication use with some risk for lactation was frequent (79.6% regarding Hale’s risk categories and 12.3% regarding Brazilian Ministry of Health criteria). We did not find statistically significant differences for weaning at 6 or 12 months between the group who did not use medication or used only compatible medications and the group who used medications with some risk for lactation, according to both criteria. Conclusions: Our study found no association between weaning rates across the different breastfeeding safety categories of medications in women who were still breastfeeding at three months postpartum. Therefore, women who took medications and stopped breastfeeding in the first three months postpartum because of adverse side-effects associated with medications could not be addressed in this analysis.

Suggested Citation

  • Bárbara Heather Lutz & Diego Garcia Bassani & Vanessa Iribarrem Avena Miranda & Marysabel Pinto Telis Silveira & Sotero Serrate Mengue & Tatiane da Silva Dal Pizzol & Mariângela Freitas da Silveira & , 2020. "Use of Medications by Breastfeeding Women in the 2015 Pelotas (Brazil) Birth Cohort Study," IJERPH, MDPI, vol. 17(2), pages 1-16, January.
  • Handle: RePEc:gam:jijerp:v:17:y:2020:i:2:p:568-:d:309245
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    Citations

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    Cited by:

    1. Michael Ceulemans & Veerle Foulon & Alice Panchaud & Ursula Winterfeld & Léo Pomar & Valentine Lambelet & Brian Cleary & Fergal O’Shaughnessy & Anneke Passier & Jonathan Luke Richardson & Hedvig Norde, 2022. "Self-Reported Medication Use among Pregnant and Breastfeeding Women during the COVID-19 Pandemic: A Cross-Sectional Study in Five European Countries," IJERPH, MDPI, vol. 19(3), pages 1-13, January.
    2. Cristina Canova & Anna Cantarutti, 2020. "Population-Based Birth Cohort Studies in Epidemiology," IJERPH, MDPI, vol. 17(15), pages 1-6, July.

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