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Surgical Treatment of Medication-Related Osteonecrosis of the Jaw: A Retrospective Study

Author

Listed:
  • Na Rae Choi

    (Department of Oral Maxillofacial Surgery, School of Dentistry, Pusan National University, Yangsan 50612, Korea)

  • Jung Han Lee

    (Department of Oral Maxillofacial Surgery, School of Dentistry, Pusan National University, Yangsan 50612, Korea)

  • Jin Young Park

    (Department of Oral Maxillofacial Surgery, School of Dentistry, Pusan National University, Yangsan 50612, Korea)

  • Dae Seok Hwang

    (Department of Oral Maxillofacial Surgery, School of Dentistry, Pusan National University, Yangsan 50612, Korea)

Abstract

The purpose of this study was to confirm the success rate of surgical treatment of medication-related osteonecrosis of the jaw (MRONJ) in patients at a single institution (Association of Oral and Maxillofacial Surgery (AAOMS) stages 1, 2, or 3), and to identify the factors that influence treatment outcomes. As a result of analyzing the outcomes of treatment, surgical “success” was achieved in 93.97% (109) of cases, and “failure” was observed at 6.03% (7) cases. Analysis of patient factors that potentially affect treatment outcomes showed that zoledronate dose ( p = 0.005) and the IV (intravenous) injection of drugs ( p = 0.044) had significant negative impacts.

Suggested Citation

  • Na Rae Choi & Jung Han Lee & Jin Young Park & Dae Seok Hwang, 2020. "Surgical Treatment of Medication-Related Osteonecrosis of the Jaw: A Retrospective Study," IJERPH, MDPI, vol. 17(23), pages 1-9, November.
    • Handle: RePEc:gam:jijerp:v:17:y:2020:i:23:p:8801-:d:451828
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