Effects of Pre-Workout Multi-Ingredient Supplement on Anaerobic Performance: Randomized Double-Blind Crossover Study

Background: The purpose of this research was to investigate the acute effects of a pre-workout supplement on anaerobic performance in resistance-trained men. Methods: Twenty-three men underwent three randomized, double-blind testing sessions separated by a seven-day break. The participants performed three tests: isokinetic strength, three repetition maximum (3-RM) strength and Wingate. Statistical analysis was conducted in R environment. Linear mixed models were estimated via R package lme4. Results: Mean T@0.2 s was significantly greater in supplemented condition for right and left knee flexors (PL: 103.2 ± 37.6 Nm; supplemented condition: 131.8 ± 29.3 Nm ( p = 0.001)), and PL: 103.7 ± 39.3; supplemented condition: 129.4 ± 28.4 ( p = 0.001)). T@0.2 s for right and left knee extensors (PL: 202.6 ± 58.6 Nm; supplemented condition: 237.2 ± 54.7 Nm ( p = 0.001); PL: 203.3 ± 63.2 Nm, supplemented condition: 229.8 ± 50.8 Nm ( p = 0.002)). Significant difference was in mean anaerobic power between supplemented and PL condition for right and left knee flexors ( p = 0.002, p = 0.005) and for right and left knee extensors ( p = 0.001 and p = 0.002). TTP was significantly shorter in supplemented condition for both sides knee flexors ( p = 0.002). There was a significant difference for mean power in the Wingate test (placebo: 8.5 ± 0.6 W/kg; supplemented condition: 8.7 ± 0.5 W/kg ( p = 0.038)). Mean 3-RM was significantly greater in supplemented condition ( p = 0.001). Conclusions: The supplement significantly improves upper and lower body strength and power output in resistance-trained men.