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Responders to Exercise Therapy in Patients with Osteoarthritis of the Hip: A Systematic Review and Meta-Analysis

Author

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  • Carolien H. Teirlinck

    (Department of General Practice, Erasmus MC University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands)

  • Arianne P. Verhagen

    (Department of General Practice, Erasmus MC University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands
    Discipline of Physiotherapy, Graduate School of Health, University of Technology Sydney, Ultimo, NSW 2007, Australia)

  • Elja A.E. Reijneveld

    (Department of General Practice, Erasmus MC University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands)

  • Jos Runhaar

    (Department of General Practice, Erasmus MC University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands)

  • Marienke van Middelkoop

    (Department of General Practice, Erasmus MC University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands)

  • Leontien M. van Ravesteyn

    (Discipline of Physiotherapy, Graduate School of Health, University of Technology Sydney, Ultimo, NSW 2007, Australia)

  • Lotte Hermsen

    (National Health Care Institute, 1110 AH Diemen, The Netherlands)

  • Ingrid B. de Groot

    (National Health Care Institute, 1110 AH Diemen, The Netherlands)

  • Sita M.A. Bierma-Zeinstra

    (Department of General Practice, Erasmus MC University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands
    Department of Orthopedics, Erasmus MC University Medical Center Rotterdam, 3000 CA Rotterdam, The Netherlands)

Abstract

The Outcome Measures in Rheumatology workgroup (OMERACT), together with the Osteoarthritis Research Society International (OARSI) developed the OMERACT-OARSI responder criteria. These criteria are used to determine if a patient with osteoarthritis (OA) ‘responds’ to therapy, meaning experiences a clinically relevant effect of therapy. Recently, more clinical OA trials report on this outcome and most OA trials have data to calculate the number of responders according to these criteria. A systematic review and meta-analysis were performed on the response to exercise therapy, compared to no or minimal intervention in patients with hip OA using the OMERACT-OARSI responder criteria. The literature was searched for relevant randomized trials. If a trial fit the inclusion criteria, but number of responders was not reported, the first author was contacted. This way the numbers of responders of 14 trials were collected and a meta-analysis on short term (directly after treatment, 12 trials n = 1178) and long term (6–8 months after treatment, six trials n = 519) outcomes was performed. At short term, the risk difference (RD) was 0.14 (95% confidence interval (CI) 0.06–0.22) and number needed to treat (NNT) 7.1 (95% CI 4.5–17); at long term RD was 0.14 (95% CI 0.07–0.20) and NNT 7.1 (95% CI 5.0–14.3). Quality of evidence was moderate for the short term and high for the long term. In conclusion, 14% more hip OA patients responded to exercise therapy than to no therapy.

Suggested Citation

  • Carolien H. Teirlinck & Arianne P. Verhagen & Elja A.E. Reijneveld & Jos Runhaar & Marienke van Middelkoop & Leontien M. van Ravesteyn & Lotte Hermsen & Ingrid B. de Groot & Sita M.A. Bierma-Zeinstra, 2020. "Responders to Exercise Therapy in Patients with Osteoarthritis of the Hip: A Systematic Review and Meta-Analysis," IJERPH, MDPI, vol. 17(20), pages 1-13, October.
    • Handle: RePEc:gam:jijerp:v:17:y:2020:i:20:p:7380-:d:425769
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    Cited by:

    1. Leidy Tatiana Ordoñez-Mora & Marco Antonio Morales-Osorio & Ilem D. Rosero, 2022. "Effectiveness of Interventions Based on Pain Neuroscience Education on Pain and Psychosocial Variables for Osteoarthritis: A Systematic Review," IJERPH, MDPI, vol. 19(5), pages 1-13, February.

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