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Association of Self-Reported Medication Adherence with Potentially Inappropriate Medications in Elderly Patients: A Cross-Sectional Pilot Study

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  • Motoyasu Miyazaki

    (Department of Pharmaceutical and Health Care Management, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka 814-0180, Japan
    Department of Pharmacy, Fukuoka University Chikushi Hospital, Chikushino 818-8502, Japan)

  • Masanobu Uchiyama

    (Department of Pharmacy, Fukuoka University Chikushi Hospital, Chikushino 818-8502, Japan)

  • Yoshihiko Nakamura

    (Department of Emergency and Critical Care Medicine, Faculty of Medicine, Fukuoka University, Fukuoka 814-0180, Japan)

  • Koichi Matsuo

    (Department of Pharmaceutical and Health Care Management, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka 814-0180, Japan
    Department of Pharmacy, Fukuoka University Chikushi Hospital, Chikushino 818-8502, Japan)

  • Chika Ono

    (Department of Pharmacy, Fukuoka University Chikushi Hospital, Chikushino 818-8502, Japan
    Department of Pharmacy, Oita Nakamura Hospital, Oita 870-0022, Japan)

  • Miwa Goto

    (Department of Pharmacy, Fukuoka University Chikushi Hospital, Chikushino 818-8502, Japan)

  • Ayako Unoki

    (Department of Pharmacy, Fukuoka University Chikushi Hospital, Chikushino 818-8502, Japan)

  • Akio Nakashima

    (Department of Pharmaceutical and Health Care Management, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka 814-0180, Japan
    Department of Pharmacy, Fukuoka University Chikushi Hospital, Chikushino 818-8502, Japan)

  • Osamu Imakyure

    (Department of Pharmaceutical and Health Care Management, Faculty of Pharmaceutical Sciences, Fukuoka University, Fukuoka 814-0180, Japan
    Department of Pharmacy, Fukuoka University Chikushi Hospital, Chikushino 818-8502, Japan)

Abstract

Background: Polypharmacy (PP) and potentially inappropriate medications (PIMs) cause problematic drug-related issues in elderly patients; however, little is known about the association between medication adherence and PP and PIMs. This study evaluated the association of self-reported medication adherence with PP and PIMs in elderly patients. Methods: A cross-sectional pilot study was conducted using data collected from electronic medical records of 142 self-administering patients aged ≥65 years, excluding emergency hospitalization cases. Self-reported medication adherence was assessed using the visual analogue scale (VAS). Results: Of the 142 patients, 91 (64.1%) had PP and 80 (56.3%) used at least one PIM. In univariate analysis, patients with a VAS score of 100% had a significantly higher number of female patients and ≥1 PIM use compared to other patients. We found no association between the VAS score and PP. In multivariable analysis, the use of PIMs was significantly associated with a VAS score of 100% (odds ratio = 2.32; 95% confidence interval = 1.16–4.72; p = 0.017). Conclusions: Use of PIMs by elderly patients is significantly associated with self-reported medication adherence. Pharmacists should pay more attention to prescribed medications of self-administering elderly patients in order to improve their prescribing quality.

Suggested Citation

  • Motoyasu Miyazaki & Masanobu Uchiyama & Yoshihiko Nakamura & Koichi Matsuo & Chika Ono & Miwa Goto & Ayako Unoki & Akio Nakashima & Osamu Imakyure, 2020. "Association of Self-Reported Medication Adherence with Potentially Inappropriate Medications in Elderly Patients: A Cross-Sectional Pilot Study," IJERPH, MDPI, vol. 17(16), pages 1-13, August.
    • Handle: RePEc:gam:jijerp:v:17:y:2020:i:16:p:5940-:d:399619
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    References listed on IDEAS

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    1. Tzu-Chueh Wang & Pou-Jen Ku & Hai-Lin Lu & Kung-Chuan Hsu & Damien Trezise & Hue-Yu Wang, 2019. "Association between Potentially Inappropriate Medication Use and Chronic Diseases in the Elderly," IJERPH, MDPI, vol. 16(12), pages 1-12, June.
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