IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v16y2019i24p4911-d294354.html
   My bibliography  Save this article

Effects of Nigella Sativa on Type-2 Diabetes Mellitus: A Systematic Review

Author

Listed:
  • Amiza Hamdan

    (Department of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia)

  • Ruszymah Haji Idrus

    (Department of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia)

  • Mohd Helmy Mokhtar

    (Department of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia)

Abstract

Diabetes mellitus is one of the most prevalent metabolic disorders that affect people of all genders, ages, and races. Medicinal herbs have gained wide attention from researchers and have been considered to be a beneficial adjuvant agent to oral antidiabetic drugs because of their integrated effects. Concerning the various beneficial effects of Nigella sativa , this systematic review aims to provide comprehensive information on the effects of Nigella sativa on glucose and insulin profile status in humans. A computerized database search performed through Scopus and Medline via Ebscohost with the following set of keywords: Nigella Sativa OR black seed oil OR thymoquinone OR black cumin AND diabetes mellitus OR hyperglycemia OR blood glucose OR hemoglobin A1C had returned 875 relevant articles. A total of seven articles were retrieved for further assessment and underwent data extraction to be included in this review. Nigella sativa was shown to significantly improve laboratory parameters of hyperglycemia and diabetes control after treatment with a significant fall in fasting blood glucose, blood glucose level 2 h postprandial, glycated hemoglobin, and insulin resistance, and a rise in serum insulin. In conclusion, these findings suggested that Nigella sativa could be used as an adjuvant for oral antidiabetic drugs in diabetes control.

Suggested Citation

  • Amiza Hamdan & Ruszymah Haji Idrus & Mohd Helmy Mokhtar, 2019. "Effects of Nigella Sativa on Type-2 Diabetes Mellitus: A Systematic Review," IJERPH, MDPI, vol. 16(24), pages 1-12, December.
    • Handle: RePEc:gam:jijerp:v:16:y:2019:i:24:p:4911-:d:294354
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/16/24/4911/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/16/24/4911/
    Download Restriction: no
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Amiza Hamdan & Ruszymah Haji Idrus & Mohd Helmy Mokhtar, 2020. "Reply to “Comment on: Effects of Nigella Sativa on Type-2 Diabetes Mellitus: A Systematic Review”," IJERPH, MDPI, vol. 17(9), pages 1-1, April.
    2. Sherif T. S. Hassan & Miroslava Šudomová, 2020. "Comment on: Effects of Nigella Sativa on Type-2 Diabetes Mellitus: A Systematic Review," IJERPH, MDPI, vol. 17(5), pages 1-2, March.

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:16:y:2019:i:24:p:4911-:d:294354. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.