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Persistent HIV Viremia: Description of a Cohort of HIV Infected Individuals with ART Failure in Puerto Rico

Author

Listed:
  • Gerónimo Maldonado-Martínez

    (Data Management and Statistical Research Support Unit, Universidad Central del Caribe, Bayamón 00960, Puerto Rico
    These authors contributed equally to this work.)

  • Robert F. Hunter-Mellado

    (Internal Medicine Department, Universidad Central del Caribe, Bayamón 00960, Puerto Rico
    These authors contributed equally to this work.)

  • Diana Fernández-Santos

    (Data Management and Statistical Research Support Unit, Universidad Central del Caribe, Bayamón 00960, Puerto Rico)

  • Eddy Ríos-Olivares

    (Microbiology Department, Universidad Central del Caribe, Bayamón 00960, Puerto Rico)

Abstract

The introduction of antiretroviral therapy (ART) has allowed human immunodeficiency virus (HIV) suppression in patients. We present data of a cohort of Puerto Rican patients with HIV who were under treatment with a steady regime of ART across a time horizon of eleven years. The time periods were categorized into four year stratums: 2000 to 2002; 2003 to 2005; 2006 to 2008 and 2009 to 2011. Socio-demographic profile, HIV risk factors, co-morbid conditions were included as study variables. One year mortality was defined. The p value was set at ≤0.05. The cohort consisted of 882 patients with 661 subjects presenting with persistent HIV viral load after a self-reported 12 month history of ART use. In this sub-cohort a higher viral load was seen across time ( p < 0.05). Illicit drug use, IV drug use, alcohol use, loss of work were associated to having higher viral load means ( p < 0.05). HIV viral load mean was lower as BMI increased ( p < 0.001). It is imperative to readdress antiretroviral adherence protocols and further study ART tolerance and compliance.

Suggested Citation

  • Gerónimo Maldonado-Martínez & Robert F. Hunter-Mellado & Diana Fernández-Santos & Eddy Ríos-Olivares, 2015. "Persistent HIV Viremia: Description of a Cohort of HIV Infected Individuals with ART Failure in Puerto Rico," IJERPH, MDPI, vol. 13(1), pages 1-8, December.
  • Handle: RePEc:gam:jijerp:v:13:y:2015:i:1:p:50-:d:61065
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