IDEAS home Printed from https://ideas.repec.org/a/gam/jijerp/v12y2015i7p7899-7909d52398.html
   My bibliography  Save this article

Incidence Density and Risk Factors of Diabetic Retinopathy Within Type 2 Diabetes: A Five-Year Cohort Study in China (Report 1)

Author

Listed:
  • Lei Liu

    (Department of Ophthalmology, The First Affiliated Hospital of China Medical University, Shenyang, 110001, China
    These authors contributed equally to this work.)

  • Jingyang Wu

    (Department of Ophthalmology, The First Affiliated Hospital of China Medical University, Shenyang, 110001, China
    These authors contributed equally to this work.)

  • Song Yue

    (Department of Ophthalmology, The First Affiliated Hospital of China Medical University, Shenyang, 110001, China)

  • Jin Geng

    (Department of Ophthalmology, The First Affiliated Hospital of China Medical University, Shenyang, 110001, China)

  • Jie Lian

    (Department of Healthcenter, Fengyutan Community, Shenyang, 110014, China)

  • Weiping Teng

    (Key Laboratory of Endocrine Diseases in Liaoning Province, The First Hospital of China Medical University, Shenyang, 110001, China)

  • Desheng Huang

    (Department of Epidemiology, School of Public Health, China Medical University, Shenyang, 110122, China)

  • Lei Chen

    (Department of Ophthalmology, The First Affiliated Hospital of China Medical University, Shenyang, 110001, China
    Key Laboratory of Endocrine Diseases in Liaoning Province, The First Hospital of China Medical University, Shenyang, 110001, China)

Abstract

A prospective study was carried out from August 2010 to August 2014 in the community of Fengyutan (China). Six hundred and twenty two T2D subjects were collected. The incidence density of diabetic retinopathy (DR) was 1.81% person-year (95% confidence interval, CI: 1.21–2.43% person-year). After a Cox regression model analysis and adjusted confounding factors, independent predictors related to the incidence of DR including male gender (adjusted hazard ratios, aHR: 1.47, 95% CI: 1.21–1.62), with hypertension (aHR: 1.49, 95%: 1.12–1.73), duration of diabetes > 10 years (aHR: 2.28, 95%: 2.05–2.42), uncontrolled diabetes (aHR: 1.76, 95%: 1.41–2.01), total cholesterol ≥ 200 mg/dL (aHR: 1.54, 95%: 1.34–1.72) and HbA1c ≥ 7% (mmol/mol) (aHR: 2.12, 95%: 1.87–2.32). Duration of T2D revealed the significantly dose-response relationship to the onset of DR. The incidence density of DR in the Chinese community was relatively low in comparison with other studies. More attention should be paid to the T2D patients, especially of male gender, with hypertension, longer duration of diabetes, uncontrolled diabetes, total cholesterol ≥ 200mg/dL and HbA1c ≥ 7% (mmol/mol).

Suggested Citation

  • Lei Liu & Jingyang Wu & Song Yue & Jin Geng & Jie Lian & Weiping Teng & Desheng Huang & Lei Chen, 2015. "Incidence Density and Risk Factors of Diabetic Retinopathy Within Type 2 Diabetes: A Five-Year Cohort Study in China (Report 1)," IJERPH, MDPI, vol. 12(7), pages 1-11, July.
    • Handle: RePEc:gam:jijerp:v:12:y:2015:i:7:p:7899-7909:d:52398
    as

    Download full text from publisher

    File URL: https://www.mdpi.com/1660-4601/12/7/7899/pdf
    Download Restriction: no
    File URL: https://www.mdpi.com/1660-4601/12/7/7899/
    Download Restriction: no
    ---><---

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:gam:jijerp:v:12:y:2015:i:7:p:7899-7909:d:52398. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: MDPI Indexing Manager (email available below). General contact details of provider: https://www.mdpi.com .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.