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Design and Experimental Approach to the Construction of a Human Signal-Molecule-Profiling Database

Author

Listed:
  • Xinyan Zhao

    (Department of Micro and Nano Systems Technology (IMST), Faculty of Technology and Maritime Sciences (TekMar), Vestfold University College (HiVE), Tønsberg, N3103, Norway)

  • Tao Dong

    (Department of Micro and Nano Systems Technology (IMST), Faculty of Technology and Maritime Sciences (TekMar), Vestfold University College (HiVE), Tønsberg, N3103, Norway)

Abstract

The human signal-molecule-profiling database (HSMPD) is designed as a prospective medical database for translational bioinformatics (TBI). To explore the feasibility of low-cost database construction, we studied the roadmap of HSMPD. A HSMPD-oriented tool, called “signal-molecule-profiling (SMP) chip” was developed for data acquisition, which can be employed in the routine blood tests in hospitals; the results will be stored in the HSMPD system automatically. HSMPD system can provide data services for the TBI community, which generates a stable income to support the data acquisition. The small-scale experimental test was performed in the hospital to verify SMP chips and the demo HSMPD software. One hundred and eighty nine complete SMP records were collected, and the demo HSMPD system was also evaluated in the survey study on patients and doctors. The function of SMP chip was verified, whereas the demo HSMPD software needed to be improved. The survey study showed that patients would only accept free tests of SMP chips when they originally needed blood examinations. The study indicated that the construction of HSMPD relies on the self-motivated cooperation of the TBI community and the traditional healthcare system. The proposed roadmap potentially provides an executable solution to build the HSMPD without high costs.

Suggested Citation

  • Xinyan Zhao & Tao Dong, 2013. "Design and Experimental Approach to the Construction of a Human Signal-Molecule-Profiling Database," IJERPH, MDPI, vol. 10(12), pages 1-22, December.
    • Handle: RePEc:gam:jijerp:v:10:y:2013:i:12:p:6887-6908:d:31159
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    References listed on IDEAS

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    1. Reuben Thomas & Jimmy Phuong & Cliona M. McHale & Luoping Zhang, 2012. "Using Bioinformatic Approaches to Identify Pathways Targeted by Human Leukemogens," IJERPH, MDPI, vol. 9(7), pages 1-25, July.
    2. Xinyan Zhao & Tao Dong, 2013. "A Microfluidic Device for Continuous Sensing of Systemic Acute Toxicants in Drinking Water," IJERPH, MDPI, vol. 10(12), pages 1-16, December.
    3. Po-Hsun Cheng & Bor-Shing Lin & Chu Yu & Shun-Hsiang Hu & Sao-Jie Chen, 2013. "A Seamless Ubiquitous Telehealthcare Tunnel," IJERPH, MDPI, vol. 10(8), pages 1-17, August.
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