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Nanomaterials and Oxidative Stress

Author

Listed:
  • Vytas Reipa

    (Materials Measurement Laboratory, National Institute of Standards and Technology, 100 Bureau Dr., Gaithersburg, MD 20899, USA)

  • Donald H. Atha

    (Materials Measurement Laboratory, National Institute of Standards and Technology, 100 Bureau Dr., Gaithersburg, MD 20899, USA)

Abstract

With the rapid development of new nanomaterials, it was recognized early that together with their beneficial properties, nanomaterials may pose a risk to human health and the environment. Evidence has accumulated over the last twenty years in support of oxidative stress as a broad mechanistic concept to explain the interaction of engineered nanoparticles with biological substances. As oxidative stress as a physiological response was recognized in redox biology, its wide-ranging use in nanotoxicology has exposed new challenges and limitations. In this commentary, we review certain oxidative stress concepts and their relevance to nanotoxicology.

Suggested Citation

  • Vytas Reipa & Donald H. Atha, 2018. "Nanomaterials and Oxidative Stress," Challenges, MDPI, vol. 9(1), pages 1-6, April.
    • Handle: RePEc:gam:jchals:v:9:y:2018:i:1:p:17-:d:139293
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