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Explainable AI (XAI) in Healthcare: Building Trust in Medical Diagnosis Systems

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  • Prajakta Sudhir Khade

Abstract

Artificial Intelligence (AI) has emerged as a transformative force in healthcare, enabling highly accurate diagnoses through advanced medical imaging modalities such as computed tomography (CT), magnetic resonance imaging (MRI), and X-rays. Despite the superior performance of deep learning models, their “black-box” nature poses challenges for clinical adoption due to limited transparency and interpretability. Explainable AI (XAI) addresses these limitations by elucidating the decision-making processes of AI systems, thereby enhancing trust, accountability, and user confidence in medical applications. Techniques such as SHAP (SHapley Additive Explanations), LIME (Local Interpretable Model-Agnostic Explanations), and Grad-CAM (Gradient-weighted Class Activation Mapping) have become integral in interpreting model predictions for critical tasks like tumor detection and pulmonary disease classification. By facilitating model transparency and interpretability, XAI empowers healthcare professionals to validate AI-driven insights, ensuring safer and more reliable decision-making. Furthermore, XAI supports the ethical deployment of AI by promoting fairness, regulatory compliance, and effective human-AI collaboration. As AI continues to advance within clinical environments, XAI remains pivotal in fostering trust and ensuring the responsible, interpretable, and effective integration of AI technologies in healthcare.

Suggested Citation

  • Prajakta Sudhir Khade, 2025. "Explainable AI (XAI) in Healthcare: Building Trust in Medical Diagnosis Systems," International Journal of Scientific Research in Science and Technology, Technoscience Academy, vol. 12(6), pages 07-22, December.
  • Handle: RePEc:etm:ijsrst:v12:y2025:i6:id:1250
    DOI: 10.32628/IJSRST25126288
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