IDEAS home Printed from https://ideas.repec.org/a/epw/ejmed0/v8y2026i2id70236.html

Erectile Dysfunction Evaluation in Diabetic Patients Using SGLT-2 Inhibitors

Author

Listed:
  • Deniz Incaman

    (Baskent University, Turkiye / Adana Dr. Turgut Noyan Education and Training Hospital, Turkiye)

Abstract

Introduction: Erectile dysfunction (ED) is a common and multifactorial complication of type 2 diabetes mellitus (T2DM). It is largely driven by endothelial dysfunction, impaired nitric oxide bioavailability, and microvascular damage. While sodium–glucose cotransporter 2 (SGLT-2) inhibitors have atherosclerotic cardiovascular and metabolic benefits, their effects on erectile function remain poorly explored. Aim: The primary aim is to evaluate the effects of dapagliflozin and empagliflozin on erectile function in male patients with T2DM. Methods: This prospective observational study included 100 male patients with T2DM and severe ED. Patients received either dapagliflozin 10 mg/day or empagliflozin 25 mg/day and were followed for 6 months. Erectile function was evaluated with the International Index of Erectile Function-5 (IIEF-5) questionnaire and penile Doppler ultrasound, both at baseline and at follow-up. Results: Both treatment groups showed significant improvement in erectile function after six months. The mean IIEF-5 score increased by 171% in the dapagliflozin group and by 197% in the empagliflozin group compared with baseline values (p

Suggested Citation

  • Deniz Incaman, 2026. "Erectile Dysfunction Evaluation in Diabetic Patients Using SGLT-2 Inhibitors," European Journal of Medical and Health Sciences, European Open Science, vol. 8(2), pages 90-94, March.
    • Handle: RePEc:epw:ejmed0:v:8:y:2026:i:2:id:70236
    DOI: 10.24018/ejmed.2026.8.2.70236
    as

    Download full text from publisher

    File URL: https://eu-opensci.org/index.php/ejmed/article/view/70236
    File Function: Abstract page
    Download Restriction: no
    File URL: https://eu-opensci.org/index.php/ejmed/article/download/70236/14088
    File Function: Full text
    Download Restriction: no
    File URL: https://libkey.io/10.24018/ejmed.2026.8.2.70236?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    More about this item

    Keywords

    ;
    ;
    ;

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:epw:ejmed0:v:8:y:2026:i:2:id:70236. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Support (email available below). General contact details of provider: https://eu-opensci.org/index.php/ejmed .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.