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Effect of Autologous Platelet-Rich Plasma (PRP) on Endometrial Thickness of Wistar Rats Under Antagonist Protocol in In Vitro Fertilization

Author

Listed:
  • Anak Agung Ngurah Anantasika

    (Fertility and Reproductive Endocrinology Subspecialty, Department of Obstetrics and Gynecology, Faculty of Medicine, Udayana University, Indonesia)

  • Anom Suardika

    (Fertility and Reproductive Endocrinology Subspecialty, Department of Obstetrics and Gynecology, Faculty of Medicine, Udayana University, Indonesia)

  • Anak Agung Gde Kiki Sanjaya Dharma

    (Department of Obstetrics and Gynecology, Faculty of Medicine, Udayana University, Indonesia)

Abstract

Introduction:The advancement of Assisted Reproductive Technology (ART) has significantly improved fertility outcomes, particularly through In Vitro Fertilization (IVF). One critical factor influencing IVF success is the health and receptivity of the endometrium. This study aimed to evaluate the effect of Autologous Platelet-Rich Plasma (PRP) on endometrial thickness in Wistar rats subjected to an antagonist protocol during IVF. Methods:This experimental study used a randomized post-test only con- trolled group design involving 40 Wistar rats, divided into two groups: the treatment group (administered PRP) and the control group (no PRP admin- istration). Endometrial thickness was measured using histomorphometry, and the results were analyzed using the Mann-Whitney test. Result: A total of 40 rats were included in the study. PRP administration significantly increased endometrial thickness in rats subjected to the IVF antagonist protocol compared to the control group (p

Suggested Citation

  • Anak Agung Ngurah Anantasika & Anom Suardika & Anak Agung Gde Kiki Sanjaya Dharma, 2024. "Effect of Autologous Platelet-Rich Plasma (PRP) on Endometrial Thickness of Wistar Rats Under Antagonist Protocol in In Vitro Fertilization," European Journal of Medical and Health Sciences, European Open Science, vol. 6(6), pages 82-84, October.
    • Handle: RePEc:epw:ejmed0:v:6:y:2024:i:6:id:42227
    DOI: 10.24018/ejmed.2024.6.6.2227
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