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Multiple Intracranial Germinomas: A Case Report

Author

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  • Abdelhamid Jehri

    (Department of Neurosurgery, Ibn Rochd University Hospital, Morocco)

  • Salma Lahlou

    (Department of Neurosurgery, Ibn Rochd University Hospital, Morocco)

  • Karim Baayoud

    (Department of Neurosurgery, Ibn Rochd University Hospital, Morocco)

  • Abderrazak Bertal

    (Department of Neurosurgery, Ibn Rochd University Hospital; Laboratory of Research on Neurology, Neurosensorial Diseases and Disability, Faculty of Medicine, Hassan II University, Morocco)

  • Khadija Ibahioin

    (Department of Neurosurgery, Ibn Rochd University Hospital; Laboratory of Research on Neurology, Neurosensorial Diseases and Disability, Faculty of Medicine, Hassan II University, Morocco)

  • Abdelhakim Lakhdar

    (Department of Neurosurgery, Ibn Rochd University Hospital; Laboratory of Research on Neurology, Neurosensorial Diseases and Disability, Faculty of Medicine, Hassan II University, Morocco)

Abstract

Germinomas are malignant tumors derived from primitive germ cells located in the midline structures of the brain, namely the pineal and/or sellar region. We report a case of multiple localization of germinoma in a 21-year-old patient with moderate headache of progressive onset; complicated by bilateral ptosis, right hyperacusis and swallowing and walking disorders. Brain MRI showed multiple diffuse nodular lesions above and below the tentorial level. Tumor markers screened in the blood were negative. The patient underwent an endoscopic biopsy and a ventriculoperitoneal shunt. Anatomopathological and immunohistochemical examination confirmed the diagnosis of germinoma. The postoperative evolution was favorable and the patient was scheduled for adjuvant treatment with chemotherapy and radiotherapy. Metastatic germinomas are sensitive to radiotherapy and chemotherapy. The surgical approach is mainly used for histological diagnosis.

Suggested Citation

  • Abdelhamid Jehri & Salma Lahlou & Karim Baayoud & Abderrazak Bertal & Khadija Ibahioin & Abdelhakim Lakhdar, 2024. "Multiple Intracranial Germinomas: A Case Report," European Journal of Medical and Health Sciences, European Open Science, vol. 6(4), pages 94-95, June.
  • Handle: RePEc:epw:ejmed0:v:6:y:2024:i:4:id:42121
    DOI: 10.24018/ejmed.2024.6.4.2121
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