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Glioblastoma in a Patient with Neurofibromatosis Type 1: A Case Report and Literature Review

Author

Listed:
  • Meriem Ait Alla

    (Hassan II University, Morocco)

  • Tarik Chekrine

    (Hassan II University, Morocco)

  • Zineb Bouchbika

    (Hassan II University, Morocco)

  • Nadia Benchakroun

    (Hassan II University, Morocco)

  • Hassan Jouhadi

    (Hassan II University, Morocco)

  • Nezha Tawfiq

    (Hassan II University, Morocco)

  • Ibtissam Rezzouki

    (Hassan II University, Morocco)

  • Mehdi Karkouri

    (Hassan II University, Morocco)

  • Hakim Lakhdar

    (Hassan IIUniversity, Morocco)

  • Souha Sahraoui

    (Hassan II University, Morocco)

Abstract

Neurofibromatosis type 1 (NF1) is an autosomal dominant inherited affection characterized by a higher chance of development of tumors. There have been only few cases of glioblastoma (GBM) in adult NF1 patients. In this paper, we present the case of 43 years old patient who presented initially amnesia and seizures. The patient underwent gross total surgical excision, followed by the Stupp protocol. He received concomitant chemo-radiotherapy with temozolomide then adjuvant temozolomide chemotherapy. We have also reviewed the literature and reported the cases of GBM in NF1 patients previously published.

Suggested Citation

  • Meriem Ait Alla & Tarik Chekrine & Zineb Bouchbika & Nadia Benchakroun & Hassan Jouhadi & Nezha Tawfiq & Ibtissam Rezzouki & Mehdi Karkouri & Hakim Lakhdar & Souha Sahraoui, 2023. "Glioblastoma in a Patient with Neurofibromatosis Type 1: A Case Report and Literature Review," European Journal of Medical and Health Sciences, European Open Science, vol. 5(5), pages 29-33, September.
    • Handle: RePEc:epw:ejmed0:v:5:y:2023:i:5:id:41891
    DOI: 10.24018/ejmed.2023.5.5.1891
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