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Laryngeal NK/T Cell Lymphoma, Nasal Type: Case Report and Literature Review

Author

Listed:
  • Tarik Chekrine

    (Hassan II University, Morocco)

  • Mouna Bourhafour

    (Hassan II University, Morocco)

  • Chorouk Moustakbal

    (Hassan II University, Morocco)

  • Zineb Bouchbika

    (Hassan II University, Morocco)

  • Nadia Benchakroun

    (Hassan II University, Morocco)

  • Hassan Jouhadi

    (Hassan II University, Morocco)

  • Nezha Tawfiq

    (Hassan II University, Morocco)

  • Lamia Jabri

    (Center for Specialized Pathology, Morocco)

  • Mohamed Mahtar

    (Hassan II University, Morocco)

  • Abdellah Madani

    (Hassan II University, Morocco)

  • Souha Sahraoui

    (Hassan II University, Morocco)

Abstract

Extranodal Natural Killer T-cell lymphoma, nasal type represent a rare and aggressive entity of the non-Hodgkin's lymphomas. Laryngeal localization is rare and has a poor prognosis. We report the case of a 66-year-old patient who consulted for dyspnea, dysphonia and dysphagia. Endoscopic examination revealed an endo-laryngeal lesion. Anatomopathological study with immunohistochemistry concluded to a peripheral T NK/T-cell lymphoma nasal type. The extension workup was without abnormalities. Induction chemotherapy without anthracyclines was administered followed by conformal radiotherapy with intensity modulation in arctotherapy. Significant advances have been made over the past decade including better clarification of clinical heterogeneity, more accurate classification using imaging modalities, establishment of new prognostic models, and sequential use of anthracycline-free radiotherapy and chemotherapy in early stages and risk-adapted first-line treatment strategies in advanced stages.

Suggested Citation

  • Tarik Chekrine & Mouna Bourhafour & Chorouk Moustakbal & Zineb Bouchbika & Nadia Benchakroun & Hassan Jouhadi & Nezha Tawfiq & Lamia Jabri & Mohamed Mahtar & Abdellah Madani & Souha Sahraoui, 2023. "Laryngeal NK/T Cell Lymphoma, Nasal Type: Case Report and Literature Review," European Journal of Medical and Health Sciences, European Open Science, vol. 5(3), pages 17-21, April.
    • Handle: RePEc:epw:ejmed0:v:5:y:2023:i:3:id:41668
    DOI: 10.24018/ejmed.2023.5.3.1668
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