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High Apoptotic Index in Amniotic Membrane of Pregnant Women is A Risk Factor for Preterm Labor

Author

Listed:
  • Anak Agung Gede Putra Wiradnyana

    (Udayana University, Indonesia)

  • Anak Agung Ngurah Jaya Kusuma

    (Udayana University, Indonesia)

  • Anak Agung Ngurah Anantasika

    (Udayana University, Indonesia)

  • I Made Darmayasa

    (Udayana University, Indonesia)

  • Ryan Saktika Mulyana

    (Udayana University, Indonesia)

  • Gde Bagus Rizky Kornia

    (Udayana University, Indonesia)

Abstract

This study aims to prove a high apoptotic index in the amniotic membrane as a risk factor for preterm Labor. Case-control study, comparing preterm and term groups (n=54) who underwent labor in Obstetrics Emergency Room, Sanglah Central General Hospital Denpasar, Bali. Apoptotic index is a method of identifying and assessing the quantity of tissue undergoing apoptosis, which in this study was the amniotic membrane tissue, calculated and stained using the TUNEL method. Data collected was subjected to further statistical tests. Normality test with Shapiro Wilk test, followed by parametric independent T-test and Mann Whitney test was performed. Cut off apoptotic index was determined using the Receiver Operating Characteristic (ROC) curve. Bivariate analysis with Chi-square test and calculation of odds ratio was performed to assess the high apoptotic index to the risk of preterm Labor. Statistical significance was obtained with p value

Suggested Citation

  • Anak Agung Gede Putra Wiradnyana & Anak Agung Ngurah Jaya Kusuma & Anak Agung Ngurah Anantasika & I Made Darmayasa & Ryan Saktika Mulyana & Gde Bagus Rizky Kornia, 2023. "High Apoptotic Index in Amniotic Membrane of Pregnant Women is A Risk Factor for Preterm Labor," European Journal of Medical and Health Sciences, European Open Science, vol. 5(3), pages 79-85, April.
    • Handle: RePEc:epw:ejmed0:v:5:y:2023:i:3:id:41460
    DOI: 10.24018/ejmed.2023.5.3.1460
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