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Ozone Injection Therapy Compared with Corticosteroid Injections for Knee Osteoarthritis

Author

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  • Mustafa Yassin

    (Tel Aviv University, Israel)

  • Muhammad Khatib

    (Tel Aviv University, Israel)

  • Mohamad Eisa

    (Tel Aviv University, Israel)

  • Tomer Gazit

    (Tel Aviv University, Israel)

  • Dror Robinson

    (Tel Aviv University, Israel)

Abstract

Background: Ozone therapy has been utilized for over a hundred years for multiple indications, one of which is knee osteoarthritis. The current study compared the effect of ozone injections versus the current standard of care (corticosteroid injections) on knee pain. The study focuses on pain reduction, functionality, and quality of life. Methods: In this temporally stratified, single-blinded, controlled clinical trial, 40 patients with symptomatic knee osteoarthritis (OA) were stratified into two groups receiving intra-articular 30 μg/ml of ozone (OZ) or steroids (GS) for 3 weeks. The efficacy outcomes for knee OA were the Visual Analogue Scale (VAS), SF-12 KOOS. Patients were followed up for up to 6 months. Results: After 6 weeks from first injection, VAS score in the ozone group declined more than in the corticosteroid injection [mean inter group difference (MD) = 1.5±0.6, p

Suggested Citation

  • Mustafa Yassin & Muhammad Khatib & Mohamad Eisa & Tomer Gazit & Dror Robinson, 2022. "Ozone Injection Therapy Compared with Corticosteroid Injections for Knee Osteoarthritis," European Journal of Medical and Health Sciences, European Open Science, vol. 4(6), pages 122-128, October.
    • Handle: RePEc:epw:ejmed0:v:4:y:2022:i:6:id:41524
    DOI: 10.24018/ejmed.2022.4.6.1524
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