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Term Pregnancy Woman with Human Immunodeficiency Virus Infection and Antiretroviral Therapy as Risk Factor of High Caspase-3 Expression in Placenta

Author

Listed:
  • Denni Prasetyo

    (Sanglah General Hospital, Indonesia)

  • I Wayan Artana Putra

    (Sanglah General Hospital, Indonesia)

  • Tjokorda G. A. Suwardewa

    (Sanglah General Hospital, Indonesia)

  • I Nyoman Hariyasa Sanjaya

    (Sanglah General Hospital, Indonesia)

  • Anom Suardika

    (Sanglah General Hospital, Indonesia)

  • I Gde Sastra Winata

    (Sanglah General Hospital, Indonesia)

Abstract

Aim: To determine whether term pregnant women with human immunodeficiency virus infection who received antiretroviral therapy have a high Caspase-3 expression in the placenta. Methods: This cross-sectional analytical study was conducted at Sanglah General Hospital, Denpasar, and affiliated hospitals. Subjects were termed pregnant women with HIV (+) who received a minimum of six months of antiretroviral therapy as a risk group and pregnant women with HIV (-) as a non-risk group. Caspase-3 expression was assessed by immunohistochemical examination of placental tissue. The cut-off value for caspase-3 levels was determined by constructing a receiver operating characteristics (ROC) curve. The difference in proportion was assessed by the chi-square test, and the prevalence ratio (PR) was reported. The significance of this study was p

Suggested Citation

  • Denni Prasetyo & I Wayan Artana Putra & Tjokorda G. A. Suwardewa & I Nyoman Hariyasa Sanjaya & Anom Suardika & I Gde Sastra Winata, 2022. "Term Pregnancy Woman with Human Immunodeficiency Virus Infection and Antiretroviral Therapy as Risk Factor of High Caspase-3 Expression in Placenta," European Journal of Medical and Health Sciences, European Open Science, vol. 4(3), pages 42-45, May.
    • Handle: RePEc:epw:ejmed0:v:4:y:2022:i:3:id:41324
    DOI: 10.24018/ejmed.2022.4.3.1324
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