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Assessment of Echocardiography-Derived Total Atrial Activation Time at Patients with Type 2 Diabetes Mellitus

Author

Listed:
  • Atilla Rexhepi
  • Valon Asani
  • Hysni Ismaili
  • Fisnik Demiri
  • Vlora Ibrahimi
  • Ylber Jani

Abstract

Objectives: Atrial fibrillation (AF) is one of the main cardiovascular complications associated with type 2 diabetes mellitus (T2DM). Echocardiography-derived total atrial activation time (PA-TDI duration) which reflects electrical and structural changes to the atria, consistently and accurately predicts new-onset AF. In this study, we aimed to determine the value of PA-TDI duration in T2DM patients. Methods: A total of 40 consecutive patients with T2DM, mean age 51.5 ± 14.3 years, and 40 age and gender-matched healthy volunteers were evaluated. Conventional and tissue Doppler echocardiography were performed. Additionally, we determined the PA-TDI duration as the time interval from the onset of the P-wave in lead II of the ECG to the peak A’-wave on the tissue Doppler tracing. Results: Left atrial (LA) diameter and LA volume index were significantly higher in T2DM patients (3.36 ± 0.5 cm vs.3.10 ± 0.45cm, p=0.037; 30.8 ± 30ml/m2 vs. 29.0 ± 3.4ml/m2, p=0.03 respectively). Mitral A velocity was significantly higher in T2DM patients (69.72 ± 10.16 cm/s vs. 64.75 ± 10.64 cm/s, p=0.029). Doppler E/A ratio was lower in T2DM patients. Tissue Doppler E’/A’ ratio for left ventricular lateral annulus was significantly lower in the diabetic group (1.28±0.33 vs. 1.49±0.40, p=0.024) and E/E’ was significantly higher in the diabetic group (7.33±2.5 vs. 6.45±1.1, p=0.038). PA-TDI duration was significantly higher in the T2DM patients when compared with the controls (134.2±6.0ms vs. 124.3±9.4ms p

Suggested Citation

  • Atilla Rexhepi & Valon Asani & Hysni Ismaili & Fisnik Demiri & Vlora Ibrahimi & Ylber Jani, 2022. "Assessment of Echocardiography-Derived Total Atrial Activation Time at Patients with Type 2 Diabetes Mellitus," European Journal of Medical and Health Sciences, European Open Science, vol. 4(3), pages 23-26, May.
    • Handle: RePEc:epw:ejmed0:v:4:y:2022:i:3:id:41319
    DOI: 10.24018/ejmed.2022.4.3.1319
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    References listed on IDEAS

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    1. Wenwei Qi & Nixiao Zhang & Panagiotis Korantzopoulos & Konstantinos P Letsas & Min Cheng & Fusheng Di & Gary Tse & Tong Liu & Guangping Li, 2017. "Serum glycated hemoglobin level as a predictor of atrial fibrillation: A systematic review with meta-analysis and meta-regression," PLOS ONE, Public Library of Science, vol. 12(3), pages 1-14, March.
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