IDEAS home Printed from https://ideas.repec.org/a/epw/ejmed0/v4y2022i3id41245.html

Surveillance of Viral Hemorrhagic Fever Viruses in Lassa Fever Suspects in Ondo State, Nigeria

Author

Listed:
  • Azuka Patrick Okwuraiwe
  • Oumar Faye
  • Fehintola Anthonia Ige
  • Ayorinde Babatunde James
  • Joseph Ojonugwa Shaibu
  • Martin Faye
  • Olufemi Samuel Amoo
  • Oumar NDiaye
  • Olumuyiwa Babalola Salu
  • Sunday Aremu Omilabu
  • Rosemary Ajuma Audu

Abstract

Lassa Fever (LF) continues to be an endemic acute viral hemorrhagic fever (VHF) illness in Nigeria. Many suspected cases of LF infection have subsequently been confirmed negative and raises concerns as to what the diagnosis of such patients could be. Hence this study was to determine the causative agents of unconfirmed LF among initially suspected cases in South Western Nigeria. In this retrospective study, blood samples originally collected from 233 suspected cases of a LF outbreak response at Owo and Ose LGAs of Ondo State, were transported in triple level packaging and stored at -80°C. All samples were screened for LF IgM and IgG markers and LF PCR. Forty-five out of the stored plasma samples were randomly retrieved and analyzed for presence of IgM for seven other VHF viruses; Chikungunya (CHIK), West Nile (WN), Rift Valley fever (RVF), Yellow fever (YF), Dengue fever (DEN), Zika and Crimean-Congo hemorrhagic fever (CCHF). Out of 45 samples screened, 1 (2.2%) was positive for YF IgM antibody. The same sample was previously confirmed LF positive by PCR. This LF and YF co-infection was from a male, 23-year old individual. The presence of co-infections of LF and YF draw to limelight the need to be broad minded in exploring for the presence of other VHF viruses in outbreaks. Further studies are needed to decipher the diagnosis of LF suspected cases.

Suggested Citation

  • Azuka Patrick Okwuraiwe & Oumar Faye & Fehintola Anthonia Ige & Ayorinde Babatunde James & Joseph Ojonugwa Shaibu & Martin Faye & Olufemi Samuel Amoo & Oumar NDiaye & Olumuyiwa Babalola Salu & Sunday , 2022. "Surveillance of Viral Hemorrhagic Fever Viruses in Lassa Fever Suspects in Ondo State, Nigeria," European Journal of Medical and Health Sciences, European Open Science, vol. 4(3), pages 78-81, May.
    • Handle: RePEc:epw:ejmed0:v:4:y:2022:i:3:id:41245
    DOI: 10.24018/ejmed.2022.4.3.1245
    as

    Download full text from publisher

    File URL: https://eu-opensci.org/index.php/ejmed/article/view/41245
    File Function: Abstract page
    Download Restriction: no
    File URL: https://eu-opensci.org/index.php/ejmed/article/download/41245/9497
    File Function: Full text
    Download Restriction: no
    File URL: https://libkey.io/10.24018/ejmed.2022.4.3.1245?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Amy Maxmen, 2018. "Deadly Lassa-fever outbreak tests Nigeria's revamped health agency," Nature, Nature, vol. 555(7697), pages 421-422, March.
    2. Hannah M Edwards & Helen Counihan & Craig Bonnington & Jane Achan & Prudence Hamade & James K Tibenderana, 2021. "The impact of malaria coinfection on Ebola virus disease outcomes: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 16(5), pages 1-27, May.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.

      More about this item

      Keywords

      ;
      ;
      ;

      Statistics

      Access and download statistics

      Corrections

      All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:epw:ejmed0:v:4:y:2022:i:3:id:41245. See general information about how to correct material in RePEc.

      If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

      If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

      If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

      For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Support (email available below). General contact details of provider: https://eu-opensci.org/index.php/ejmed .

      Please note that corrections may take a couple of weeks to filter through the various RePEc services.

      IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.