IDEAS home Printed from https://ideas.repec.org/a/epw/ejmed0/v3y2021i3id40871.html

A Case of Stiffperson Syndrome

Author

Listed:
  • Mamdouh H. Kalakatawi

    (AlNoor Specialist Hospital, Kingdom of Saudi Arabia)

  • Nusrat Aziz

    (Umm AlQura University, Kingdom of Saudi Arabia)

  • Norhan A. K. Mostafa

    (Al Noor Specialists Hospital, Kingdom of Saudi Arabia)

Abstract

Stiffperson syndrome (SPS) is one of the rarest neurological disorders. It is an autoimmune disease with antibodies against glutamic acid decarboxylase - enzyme needed to produce neurotransmitter GABA. This disease is very debilitating and fatal if not managed in time. A 32-year-old man presented with stiffness of abdominal and thoracolumbar paraspinal muscles first noticed 10 months back. There was history of jerkiness of hands. After excluding other mimicking conditions like multiple sclerosis, parkinsonism and axial dystonia, a diagnosis of Stiffperson syndrome was made. Treatment with IVIG therapy along with anti-spasticity drugs resulted in improved patient outcome. SPS is potentially treatable though cannot be cured. Not one treatment fits all patients with SPS and may have to be tailored according to the clinical manifestations. Increasing awareness in medical doctors and identifying the disease early can help the patients escape the disabling effects of SPS and improve the quality of life.

Suggested Citation

  • Mamdouh H. Kalakatawi & Nusrat Aziz & Norhan A. K. Mostafa, 2021. "A Case of Stiffperson Syndrome," European Journal of Medical and Health Sciences, European Open Science, vol. 3(3), pages 52-54, May.
    • Handle: RePEc:epw:ejmed0:v:3:y:2021:i:3:id:40871
    DOI: 10.24018/ejmed.2021.3.3.871
    as

    Download full text from publisher

    File URL: https://eu-opensci.org/index.php/ejmed/article/view/40871
    File Function: Abstract page
    Download Restriction: no
    File URL: https://eu-opensci.org/index.php/ejmed/article/download/40871/9254
    File Function: Full text
    Download Restriction: no
    File URL: https://libkey.io/10.24018/ejmed.2021.3.3.871?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    More about this item

    Keywords

    ;
    ;
    ;
    ;

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:epw:ejmed0:v:3:y:2021:i:3:id:40871. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Support (email available below). General contact details of provider: https://eu-opensci.org/index.php/ejmed .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.