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Flexible Insulin Therapy: Results of a Tunisian Experience

Author

Listed:
  • Hajer Kandara

    (National institute of nutrition of Tunis, Tunisia)

  • Chaima Jemai

    (National institute of nutrition of Tunis, Tunisia)

  • Abdennebi Cyrine

    (National institute of nutrition of Tunis, Tunisia)

  • Jemel Manel

    (National institute of nutrition of Tunis, Tunisia)

  • Kammoun Ines

    (National institute of nutrition of Tunis, Tunisia)

Abstract

Aims: To evaluate the adherence of type 1 diabetic patients to long-term flexible insulin therapy (FIT), and the impact of this approach on the glycemic balance, basal insuline dose and quality of life of patients. Methods: This is a rospective descriptive study, conducted between January and April 2017, including 50 patients with type 1 diabetes having following the FIT of department B of Endocrinology-Diabetology and Metabolic Diseases service B at the National Institute of Nutrition and Food Technology of Tunis. Results: The FIT decreased mean HbA1c from 8.96% to 7.57% (p=0.04) and mean basal insulin dose from 0.35 to 0.27 IU/kg /day. Hypoglycemia's frequency decreased from 3.2±2.1 to 0.93±2.1 episodes /patient /week (p=0.03), with improved quality of life. However, there was a significant weight gain (p=0.02). Conclusions: FIT allows for better glycemic control while reducing hypoglycemia, especially severe episodes, and improves the quality of life of patients with type 1 diabetes but seems to cause weight gain.

Suggested Citation

  • Hajer Kandara & Chaima Jemai & Abdennebi Cyrine & Jemel Manel & Kammoun Ines, 2020. "Flexible Insulin Therapy: Results of a Tunisian Experience," European Journal of Medical and Health Sciences, European Open Science, vol. 2(4), July.
    • Handle: RePEc:epw:ejmed0:v:2:y:2020:i:4:id:40243
    DOI: 10.24018/ejmed.2020.2.4.243
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