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Comparative Modulation of the Reproductive System by Ethanolleaf Extracts of Asystasia Gangetica Andanthocleista Vogelli in Male Wistar Rats

Author

Listed:
  • Simeon I. Egba

    (Michael Okpara University of Agriculture, Nigeria.)

  • C. O. Okonkwo

    (University of Calabar, Nigeria.)

  • H. C. Omeoga

    (Michael Okpara University of Agriculture, Nigeria.)

  • I. E. Ekong

    (Michael Okpara University of Agriculture, Nigeria.)

Abstract

A number of medicinal plants have been found to influence the level of reproductive hormones and thus affect fertility in the overall. This work evaluated the effects of ethanol leaf extracts of A. gangetica and A. vogelli respectively on some reproductive system parameters in male Wistar rats. A total of sixteen (16) male albino rats were grouped into four (four rats in each group): group A served as normal control, group B received Immunace (Vitabiotics) group C and D received 400 mg/kg body weight of A. gangetica and A. vogelli extracts respectively. Extracts were administered orally to rats for 21 days, after which they were sacrificed by cervical dislocations and blood samples drawn by cardiac puncture. The effect of the extracts on testosterone, follicle stimulating hormone, luteinizing hormone and semen analysis of the test rats were determined using enzyme linked immunosorbent assay (ELISA) and standard techniques. Data collected were analyzed using Graph pad prism V6 and p values 0.05) change in testosterone, FSH and luteinizing hormones in the group administered A. gangetica plant extract relative to the control. There was also no visible difference in the testes weight and sperm morphology relative to the control group. In contrast, administration of A. vogelli extract caused significant (p

Suggested Citation

  • Simeon I. Egba & C. O. Okonkwo & H. C. Omeoga & I. E. Ekong, 2020. "Comparative Modulation of the Reproductive System by Ethanolleaf Extracts of Asystasia Gangetica Andanthocleista Vogelli in Male Wistar Rats," European Journal of Medical and Health Sciences, European Open Science, vol. 2(3), May.
    • Handle: RePEc:epw:ejmed0:v:2:y:2020:i:3:id:40287
    DOI: 10.24018/ejmed.2020.2.3.287
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