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The Motor Coordination Activity Of Aqueous Extract Of Withania Coagulans Fruits In Swiss Albino Mice By Rota Rod Test

Author

Listed:
  • Amit Shankarrao Kamdi

    (Sanjeevani Multipurpose Society Mul, India)

  • Devesh D. Gosavi

    (Mahatma Gandhi Institute of Medical Sciences, India)

  • Suvarna M. Kalambe

    (Sanjeevani Multipurpose Society Mul, India)

  • Pankaj N. Bohra

    (SNEH Foundation, India)

Abstract

Background: The various sedative and hypnotic medications used today have the central nervous system (CNS) depressant effects. A very little work has been done on the Withania coagulans – a vulnerable species as it is not found rampant in the world except in late seventies. Therefore, it was important to explore the CNS depressant activities of aqueous extract of Withania coagulans fruits in Swiss albino mice by using rota rod test. Methods: Motor coordination was assessed by using the Rota Rod Test. The CNS depressant drugs decrease the endurance time of mice on the rota rod as they impair the motor coordination so that mice fall early on the rotating rod. This endurance time is statistically correlated among the control, standard and the test drugs. Results: There was statistically highly significant (p-value

Suggested Citation

  • Amit Shankarrao Kamdi & Devesh D. Gosavi & Suvarna M. Kalambe & Pankaj N. Bohra, 2020. "The Motor Coordination Activity Of Aqueous Extract Of Withania Coagulans Fruits In Swiss Albino Mice By Rota Rod Test," European Journal of Medical and Health Sciences, European Open Science, vol. 2(3), May.
    • Handle: RePEc:epw:ejmed0:v:2:y:2020:i:3:id:40255
    DOI: 10.24018/ejmed.2020.2.3.255
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