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Amlodipine-induced Peri-implantitis in a Patient with Poor Oral Hygiene: A 10-year Follow-up Case Report

Author

Listed:
  • Andrea del Valle Almazán Santandreu

    (Corazon de Jesús Foundation, Argentina)

  • José Luis Calvo Guirado

    (University of Murcia, Spain)

  • Miguel Angel Garcés Villalá

    (Corazon de Jesús Foundation, Argentina)

Abstract

Gingival hyperplasia secondary to the administration of calcium channel blockers for the treatment of hypertension in dental implants has not yet been fully investigated. We present a clinical case of peri-implantitis secondary to severe gingival hyperplasia associated with amlodipine administration and its subsequent 10-year follow-up period. Postoperative maintenance therapy is crucial for preventing recurrence of drug-induced gingival hypertrophy. The patient’s commitment to maintaining excellent home oral hygiene, especially with irrigators, and their consistent attendance at every three months check-ups for examination and/or professional ultrasonic cleaning is a “conditio sine qua non” for the prevention of peri-implantitis. Amlodipine-induced peri-implant gingival hyperplasia in patients with poor oral hygiene can progress to amlodipine-induced peri-implantitis, compromising osseointegration of dental implants. However, further studies are needed to validate these findings due to the limitations of a single-case study and confounding factors associated with biomechanics.

Suggested Citation

  • Andrea del Valle Almazán Santandreu & José Luis Calvo Guirado & Miguel Angel Garcés Villalá, 2025. "Amlodipine-induced Peri-implantitis in a Patient with Poor Oral Hygiene: A 10-year Follow-up Case Report," European Journal of Dental and Oral Health, European Open Science, vol. 6(6), pages 39-43, November.
    • Handle: RePEc:epw:ejdent:v:6:y:2025:i:6:id:13420
    DOI: 10.24018/ejdent.2025.6.6.13420
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