Clinical, Radiographic, and Histological Evaluation of the Mineralized Plasmatic Matrix/Xenograft Mixture in Maxillary Sinus Floor Augmentation (A Randomized Controlled Clinical Trial)

Introduction: Maxillary sinus pneumatization and alveolar ridge resorption following the extraction of posterior teeth make the installation of dental implants in the maxillary posterior region challenging. The direct sinus lift procedure proved to be a viable treatment option for such conditions. Aim of the study: to evaluate the mineralized plasmatic matrix/xenograft mixture in sinus elevation surgery. Materials and Methods: Eighteen patients were selected and randomly allocated into two groups; study group received a mineralized plasmatic matrix/xenograft mixture, while the control group received xenograft alone following sinus lifting. Results: The early wound healing index score showed a non-significant difference between both groups. Also, bone height was evaluated at the 6-month follow-up period, and there was a non-statistically significant difference. Core biopsies were taken for histological examination by H&E from both groups, revealing the presence of a more mature bone matrix in relation to the test group. Conclusion: The addition of mineralized plasmatic matrix to xenograft can speed up bone formation, thus reducing treatment duration.