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Synthesis of α-ribonucleoside (Majority) by the Coupling of NP/KI and NP/I₂

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  • Driss Ouzebla

Abstract

In this work we will demonstrate a method of preparing α-D-ribonucleosides using the solid-phase approach using the combination between natural phosphate doped with potassium iodide (NP/KI) and natural phosphate doped with iodine (NP/I2). All these derivatives ribonucleosides were prepared by N-glycosylation reaction between silylated bases and 1-O-acétyl-2,3,5-tri-O-benzoyl-β-D-ribofuranoside.

Suggested Citation

  • Driss Ouzebla, 2020. "Synthesis of α-ribonucleoside (Majority) by the Coupling of NP/KI and NP/I₂," European Journal of Advanced Chemistry Research, European Open Science, vol. 1(6), November.
    • Handle: RePEc:epw:ejchem:v:1:y:2020:i:6:id:5030
    DOI: 10.24018/ejchem.2020.1.6.30
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