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Synthesis of α-ribonucleoside (Majority) by the Coupling of NP/KI and NP/I₂

Author

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  • Driss Ouzebla

    (Université Cadi-Ayyad, Morocco)

Abstract

In this work we will demonstrate a method of preparing α-D-ribonucleosides using the solid-phase approach using the combination between natural phosphate doped with potassium iodide (NP/KI) and natural phosphate doped with iodine (NP/I2). All these derivatives ribonucleosides were prepared by N-glycosylation reaction between silylated bases and 1-O-acétyl-2,3,5-tri-O-benzoyl-β-D-ribofuranoside.

Suggested Citation

Handle: RePEc:epw:ejchem:v:1:y:2020:i:6:id:5030
DOI: 10.24018/ejchem.2020.1.6.30
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