IDEAS home Printed from https://ideas.repec.org/a/epw/clinic/v4y2023i6id12317.html

Cytoreductive Surgery and HIPEC in Elderly Patient with Colorectal Cancer and Peritoneal Metastasis

Author

Listed:
  • Evita Gašenko

    (University of Latvia, Riga East University Hospital, Latvia)

  • Andrejs Pčolkins

    (University of Latvia, Riga East University Hospital, Latvia)

  • Inga Bogdanova

    (Riga East University Hospital, Latvia)

  • Signe Plāte

    (Riga East University Hospital, Latvia)

Abstract

Background: Colorectal cancer (CRC) patients with peritoneal metastasis have the worst prognosis with a median overall survival of 4.1–8.5 months [1],[2]. Aim: To assess results in the elderly metastatic CRC patient with peritoneal dissemination treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) with oxaliplatin. Case Presented: Patient - 70-year-old female with metastatic CRC and peritoneal carcinomatosis. Prior to surgery, received 12 of chemotherapy FOLFOX + bevacizumab. CRS + HIPEC was performed followed by an uneventful recovery. After surgery, she has received chemotherapy with FOLFIRI. The disease progressed 14 months later. The patient has continued therapy with FOLFIRI, unfortunately, the disease has progressed and oral therapy with ftorafur has commenced. Patients’ overall survival so far is 48 months. Conclusions: Even though we cannot decisively distinguish if results are determined by CRS or additional HIPEC, the presented case shows the importance of a paradigm shift when peritoneal disease in selected patients is viewed as a regional disease rather than diffuse metastatic.

Suggested Citation

  • Evita Gašenko & Andrejs Pčolkins & Inga Bogdanova & Signe Plāte, 2023. "Cytoreductive Surgery and HIPEC in Elderly Patient with Colorectal Cancer and Peritoneal Metastasis," European Journal of Clinical Medicine, European Open Science, vol. 4(6), pages 1-5, November.
    • Handle: RePEc:epw:clinic:v:4:y:2023:i:6:id:12317
    DOI: 10.24018/clinicmed.2023.4.6.317
    as

    Download full text from publisher

    File URL: https://eu-opensci.org/index.php/clinicmed/article/view/12317
    File Function: Abstract page
    Download Restriction: no
    File URL: https://eu-opensci.org/index.php/clinicmed/article/download/12317/2551
    File Function: Full text
    Download Restriction: no
    File URL: https://libkey.io/10.24018/clinicmed.2023.4.6.317?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    More about this item

    Keywords

    ;
    ;
    ;
    ;

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:epw:clinic:v:4:y:2023:i:6:id:12317. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: Support Team (email available below). General contact details of provider: https://eu-opensci.org/index.php/clinicmed .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.