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Anti-Saccharomyces cerevisiae Antibodies (ASCA) Researched by Tube Precipitins are Elevated in Patients with Dermatologic and Gastrointestinal Non-Ige-Mediated Hypersensitivity

Author

Listed:
  • Celso Eduardo Olivier

    (Instituto Alergoimuno de Americana, Brasil)

  • Daiana G. Pinto

    (Instituto Alergoimuno de Americana, Brasil)

  • Ana P. M. Teixeira

    (Instituto Alergoimuno de Americana, Brasil)

  • Jhéssica L. S. Santana

    (Instituto Alergoimuno de Americana, Brasil)

  • Raquel A. P. G. Santos

    (Instituto Alergoimuno de Americana, Brasil)

  • Regiane P. S. Lima

Abstract

Background: The presence of anti-Saccharomyces cerevisiae antibodies (ASCA) has been reported in the serum of patients with several immune-inflammatory diseases. Objective: To evaluate the presence of ASCA in patients with non-IgE-mediated hypersensitivity. Methods: A group of 222 patients with non-IgE-mediated hypersensitivity was divided into three groups according to dermatologic, gastrointestinal, and respiratory symptoms. Group D was composed of 163 patients with dermatologic symptoms diagnosed as intrinsic atopic dermatitis and/or non-IgE-mediated urticaria. Group G was composed of 23 patients diagnosed with non-IgE-mediated gastrointestinal food allergies. Group R was composed of 36 patients with respiratory symptoms diagnosed as non-IgE-mediated rhinitis and/or non-IgE-mediated asthma. Results: The Wilcoxon-Mann-Whitney U test comparing the precipitin’s titers of group G and group D showed a non-significant p-value of 0.83366. The Wilcoxon-Mann-Whitney U test comparing the precipitin’s titers of group R and group G showed a significant p-value of 0.00034. The Wilcoxon-Mann-Whitney U test comparing the precipitin’s titers of group R and group D showed a significant p-value

Suggested Citation

  • Celso Eduardo Olivier & Daiana G. Pinto & Ana P. M. Teixeira & Jhéssica L. S. Santana & Raquel A. P. G. Santos & Regiane P. S. Lima, 2023. "Anti-Saccharomyces cerevisiae Antibodies (ASCA) Researched by Tube Precipitins are Elevated in Patients with Dermatologic and Gastrointestinal Non-Ige-Mediated Hypersensitivity," European Journal of Clinical Medicine, European Open Science, vol. 4(2), pages 25-30, March.
    • Handle: RePEc:epw:clinic:v:4:y:2023:i:2:id:12223
    DOI: 10.24018/clinicmed.2023.4.2.223
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