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Strategic resource mobilization for AI entrepreneurship in healthcare: Qualitative insights from startup founders

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  • Zahlan, Ahmed

Abstract

Artificial intelligence (AI) has emerged as a critical focus for entrepreneurs, driving the development of AI-based startups to address challenges in various sectors, especially healthcare. Despite increased opportunities from greater data availability and supportive digitalization legislation, the healthcare industry remains resistant to disruptive technologies due to strict regulations. This resistance presents unique challenges for AI healthcare startups. Although literature investigates how startups handle the liability of newness and employ strategies such as using founder experience, participating in incubators, and forming alliances, little insight is provided into these challenges amidst the dual complexities of AI and healthcare. This study identifies the crucial elements for successfully launching AI healthcare startups amid multiple layers of complexity, including stringent regulations, data acquisition challenges, and advanced technology adoption. It conducts in-depth interviews with founders from 55 AI healthcare startups at various stages of development using a grounded theory approach. The findings highlight factors such as team structure, funding strategies, stakeholder engagement, and the role of data as a competitive asset. This research enriches the academic literature by deepening the understanding of success determinants in high-tech and regulated environments, challenging the jack-of-all-trades theory by underscoring the significance of diverse foundational team backgrounds, and refining the technology adoption framework by distinguishing between adoption patterns of physicians and patients. This research offers theoretical and practical contributions, aiming to foster improvements in patient care, efficiency, and overall healthcare outcomes through the innovations of AI startups.

Suggested Citation

  • Zahlan, Ahmed, 2025. "Strategic resource mobilization for AI entrepreneurship in healthcare: Qualitative insights from startup founders," Technovation, Elsevier, vol. 145(C).
  • Handle: RePEc:eee:techno:v:145:y:2025:i:c:s016649722500104x
    DOI: 10.1016/j.technovation.2025.103272
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    1. Lerner, Josh & Schoar, Antoinette & Sokolinski, Stanislav & Wilson, Karen, 2018. "The globalization of angel investments: Evidence across countries," Journal of Financial Economics, Elsevier, vol. 127(1), pages 1-20.
    2. Sebastian Krakowski & Johannes Luger & Sebastian Raisch, 2023. "Artificial intelligence and the changing sources of competitive advantage," Strategic Management Journal, Wiley Blackwell, vol. 44(6), pages 1425-1452, June.
    3. Islam, Mazhar & Fremeth, Adam & Marcus, Alfred, 2018. "Signaling by early stage startups: US government research grants and venture capital funding," Journal of Business Venturing, Elsevier, vol. 33(1), pages 35-51.
    4. Soetanto, Danny & Jack, Sarah, 2016. "The impact of university-based incubation support on the innovation strategy of academic spin-offs," Technovation, Elsevier, vol. 50, pages 25-40.
    5. Joel A. C. Baum & Tony Calabrese & Brian S. Silverman, 2000. "Don't go it alone: alliance network composition and startups' performance in Canadian biotechnology," Strategic Management Journal, Wiley Blackwell, vol. 21(3), pages 267-294, March.
    6. David H. Hsu & Rosemarie H. Ziedonis, 2013. "Resources as dual sources of advantage: Implications for valuing entrepreneurial‐firm patents," Strategic Management Journal, Wiley Blackwell, vol. 34(7), pages 761-781, July.
    7. Dwivedi, Yogesh K. & Hughes, Laurie & Ismagilova, Elvira & Aarts, Gert & Coombs, Crispin & Crick, Tom & Duan, Yanqing & Dwivedi, Rohita & Edwards, John & Eirug, Aled & Galanos, Vassilis & Ilavarasan, , 2021. "Artificial Intelligence (AI): Multidisciplinary perspectives on emerging challenges, opportunities, and agenda for research, practice and policy," International Journal of Information Management, Elsevier, vol. 57(C).
    8. Pradeep Kumar & Yogesh K. Dwivedi & Ambuj Anand, 2023. "Responsible Artificial Intelligence (AI) for Value Formation and Market Performance in Healthcare: the Mediating Role of Patient’s Cognitive Engagement," Information Systems Frontiers, Springer, vol. 25(6), pages 2197-2220, December.
    9. Ajay Khorana & Edward Nelling, 1997. "The Performance, Risk, and Diversification of Sector Funds," Financial Analysts Journal, Taylor & Francis Journals, vol. 53(3), pages 62-74, May.
    10. Sarfraz Mian & Wadid Lamine & Alain Fayolle, 2016. "Technology Business Incubation: An overview of the state of knowledge," Post-Print hal-02014389, HAL.
    11. Roure, Juan B. & Keeley, Robert H., 1990. "Predictors of success in new technology based ventures," Journal of Business Venturing, Elsevier, vol. 5(4), pages 201-220, July.
    12. Zhao, Bo & Ziedonis, Rosemarie, 2020. "State governments as financiers of technology startups: Evidence from Michigan's R&D loan program," Research Policy, Elsevier, vol. 49(4).
    13. Ting Yao & Hugh O'Neill, 2022. "Venture capital exit pressure and venture exit: A board perspective," Strategic Management Journal, Wiley Blackwell, vol. 43(13), pages 2829-2848, December.
    14. Iris Vanaelst & Bart Clarysse & Mike Wright & Andy Lockett & Nathalie Moray & Rosette S'Jegers, 2006. "Entrepreneurial Team Development in Academic Spinouts: An Examination of Team Heterogeneity," Entrepreneurship Theory and Practice, , vol. 30(2), pages 249-271, March.
    15. Nima Kordzadeh & Maryam Ghasemaghaei, 2022. "Algorithmic bias: review, synthesis, and future research directions," European Journal of Information Systems, Taylor & Francis Journals, vol. 31(3), pages 388-409, May.
    16. Michael Weber & Moritz Beutter & Jörg Weking & Markus Böhm & Helmut Krcmar, 2022. "AI Startup Business Models," Business & Information Systems Engineering: The International Journal of WIRTSCHAFTSINFORMATIK, Springer;Gesellschaft für Informatik e.V. (GI), vol. 64(1), pages 91-109, February.
    17. Hsu, David H., 2007. "Experienced entrepreneurial founders, organizational capital, and venture capital funding," Research Policy, Elsevier, vol. 36(5), pages 722-741, June.
    18. Chandler, Gaylen N. & Hanks, Steven H., 1994. "Market attractiveness, resource-based capabilities, venture strategies, and venture performance," Journal of Business Venturing, Elsevier, vol. 9(4), pages 331-349, July.
    19. Andreas Rauch & Serge A. Rijsdijk, 2013. "The Effects of General and Specific Human Capital on Long–Term Growth and Failure of Newly Founded Businesses," Entrepreneurship Theory and Practice, , vol. 37(4), pages 923-941, July.
    20. Bradonjic, Philip & Franke, Nikolaus & Lüthje, Christian, 2019. "Decision-makers’ underestimation of user innovation," Research Policy, Elsevier, vol. 48(6), pages 1354-1361.
    21. Sarfraz Mian & Wadid Lamine & Alain Fayolle, 2016. "Technology Business Incubation : An overview of the state of knowledge," Post-Print hal-02313371, HAL.
    22. Christoph Zott & Raphael Amit, 2008. "The fit between product market strategy and business model: implications for firm performance," Strategic Management Journal, Wiley Blackwell, vol. 29(1), pages 1-26, January.
    23. van Weele, Marijn & van Rijnsoever, Frank J. & Nauta, Frans, 2017. "You can't always get what you want: How entrepreneur's perceived resource needs affect the incubator's assertiveness," Technovation, Elsevier, vol. 59(C), pages 18-33.
    24. Jennifer L. Woolley & Nydia MacGregor, 2022. "The Influence of Incubator and Accelerator Participation on Nanotechnology Venture Success," Entrepreneurship Theory and Practice, , vol. 46(6), pages 1717-1755, November.
    25. Saerom (Ronnie) Lee & J. Daniel Kim, 2024. "When do startups scale? Large‐scale evidence from job postings," Strategic Management Journal, Wiley Blackwell, vol. 45(9), pages 1633-1669, September.
    26. Gimenez-Fernandez, Elena M. & Sandulli, Francesco D. & Bogers, Marcel, 2020. "Unpacking liabilities of newness and smallness in innovative start-ups: Investigating the differences in innovation performance between new and older small firms," Research Policy, Elsevier, vol. 49(10).
    27. Rosenbusch, Nina & Brinckmann, Jan & Müller, Verena, 2013. "Does acquiring venture capital pay off for the funded firms? A meta-analysis on the relationship between venture capital investment and funded firm financial performance," Journal of Business Venturing, Elsevier, vol. 28(3), pages 335-353.
    28. Mariani, Marcello M. & Machado, Isa & Magrelli, Vittoria & Dwivedi, Yogesh K., 2023. "Artificial intelligence in innovation research: A systematic review, conceptual framework, and future research directions," Technovation, Elsevier, vol. 122(C).
    29. Mikalef, Patrick & Islam, Najmul & Parida, Vinit & Singh, Harkamaljit & Altwaijry, Najwa, 2023. "Artificial intelligence (AI) competencies for organizational performance: A B2B marketing capabilities perspective," Journal of Business Research, Elsevier, vol. 164(C).
    30. Robert S. Harris & Tim Jenkinson & Steven N. Kaplan, 2014. "Private Equity Performance: What Do We Know?," Journal of Finance, American Finance Association, vol. 69(5), pages 1851-1882, October.
    31. Chang, Sea Jin, 2004. "Venture capital financing, strategic alliances, and the initial public offerings of Internet startups," Journal of Business Venturing, Elsevier, vol. 19(5), pages 721-741, September.
    32. Sipior, Janice C., 2020. "Considerations for development and use of AI in response to COVID-19," International Journal of Information Management, Elsevier, vol. 55(C).
    33. Colombo, Massimo G. & Grilli, Luca, 2010. "On growth drivers of high-tech start-ups: Exploring the role of founders' human capital and venture capital," Journal of Business Venturing, Elsevier, vol. 25(6), pages 610-626, November.
    34. Martin Obschonka & David B. Audretsch, 2020. "Artificial intelligence and big data in entrepreneurship: a new era has begun," Small Business Economics, Springer, vol. 55(3), pages 529-539, October.
    35. Stuart, Robert & Abetti, Pier A., 1987. "Start-up ventures: Towards the prediction of initial success," Journal of Business Venturing, Elsevier, vol. 2(3), pages 215-230.
    36. Yanfeng Zheng & Michael L. Devaughn & Mary Zellmer-Bruhn, 2016. "Shared and shared alike? Founders' prior shared experience and performance of newly founded banks," Strategic Management Journal, Wiley Blackwell, vol. 37(12), pages 2503-2520, December.
    37. Larrañeta, Bárbara & Zahra, Shaker A. & González, José Luis Galán, 2012. "Enriching strategic variety in new ventures through external knowledge," Journal of Business Venturing, Elsevier, vol. 27(4), pages 401-413.
    38. Bessen, James & Impink, Stephen Michael & Reichensperger, Lydia & Seamans, Robert, 2022. "The role of data for AI startup growth," Research Policy, Elsevier, vol. 51(5).
    39. Yogesh K. Dwivedi & A. Sharma & Nripendra P. Rana & M. Giannakis & P. Goel & Vincent Dutot, 2023. "Evolution of Artificial Intelligence Research in Technological Forecasting and Social Change: Research Topics, Trends, and Future Directions," Post-Print hal-04292607, HAL.
    40. Birgul Arslan, 2018. "The interplay of competitive and cooperative behavior and differential benefits in alliances," Strategic Management Journal, Wiley Blackwell, vol. 39(12), pages 3222-3246, December.
    41. Mian, Sarfraz & Lamine, Wadid & Fayolle, Alain, 2016. "Technology Business Incubation: An overview of the state of knowledge," Technovation, Elsevier, vol. 50, pages 1-12.
    42. Sandy Yu, 2020. "How Do Accelerators Impact the Performance of High-Technology Ventures?," Management Science, INFORMS, vol. 66(2), pages 530-552, February.
    43. Dwivedi, Yogesh K. & Sharma, Anuj & Rana, Nripendra P. & Giannakis, Mihalis & Goel, Pooja & Dutot, Vincent, 2023. "Evolution of artificial intelligence research in Technological Forecasting and Social Change: Research topics, trends, and future directions," Technological Forecasting and Social Change, Elsevier, vol. 192(C).
    44. Hughes, Paul & Morgan, Robert E., 2008. "Fitting strategic resources with product-market strategy: Performance implications," Journal of Business Research, Elsevier, vol. 61(4), pages 323-331, April.
    45. Chakraborty, Imon & Ilavarasan, P. Vigneswara & Edirippulige, Sisira, 2021. "Health-tech startups in healthcare service delivery: A scoping review," Social Science & Medicine, Elsevier, vol. 278(C).
    46. Cacciolatti, Luca & Rosli, Ainurul & Ruiz-Alba, José L. & Chang, Jane, 2020. "Strategic alliances and firm performance in startups with a social mission," Journal of Business Research, Elsevier, vol. 106(C), pages 106-117.
    47. Samer Faraj & Lee Sproull, 2000. "Coordinating Expertise in Software Development Teams," Management Science, INFORMS, vol. 46(12), pages 1554-1568, December.
    48. Roure, Juan B. & Maidique, Modesto A., 1986. "Linking prefunding factors and high-technology venture success: An exploratory study," Journal of Business Venturing, Elsevier, vol. 1(3), pages 295-306.
    49. Junfu Zhang, 2011. "The advantage of experienced start-up founders in venture capital acquisition: evidence from serial entrepreneurs," Small Business Economics, Springer, vol. 36(2), pages 187-208, February.
    50. Mikael Samuelsson & Anna Söderblom & Alexander McKelvie, 2021. "Path Dependence in New Ventures’ Capital Structures," Entrepreneurship Theory and Practice, , vol. 45(2), pages 319-349, March.
    51. Cavallo, Angelo & Ghezzi, Antonio & Dell'Era, Claudio & Pellizzoni, Elena, 2019. "Fostering digital entrepreneurship from startup to scaleup: The role of venture capital funds and angel groups," Technological Forecasting and Social Change, Elsevier, vol. 145(C), pages 24-35.
    52. Costa, Paula L. & Ferreira, João J. & Torres de Oliveira, Rui, 2023. "From entrepreneurial failure to re-entry," Journal of Business Research, Elsevier, vol. 158(C).
    53. Zahlan, Ahmed & Ranjan, Ravi Prakash & Hayes, David, 2023. "Artificial intelligence innovation in healthcare: Literature review, exploratory analysis, and future research," Technology in Society, Elsevier, vol. 74(C).
    54. Jukka Partanen & Sylvie K. Chetty & Arto Rajala, 2014. "Innovation Types and Network Relationships," Entrepreneurship Theory and Practice, , vol. 38(5), pages 1027-1055, September.
    55. Collins, Christopher & Dennehy, Denis & Conboy, Kieran & Mikalef, Patrick, 2021. "Artificial intelligence in information systems research: A systematic literature review and research agenda," International Journal of Information Management, Elsevier, vol. 60(C).
    56. Y. Lisa Zhao & Michael Song & Gregory L. Storm, 2013. "Founding Team Capabilities and New Venture Performance: The Mediating Role of Strategic Positional Advantages," Entrepreneurship Theory and Practice, , vol. 37(4), pages 789-814, July.
    57. van Rijnsoever, Frank J., 2020. "Meeting, mating, and intermediating: How incubators can overcome weak network problems in entrepreneurial ecosystems," Research Policy, Elsevier, vol. 49(1).
    58. Al-Tabbaa, Omar & Leach, Desmond & Khan, Zaheer, 2019. "Examining alliance management capabilities in cross-sector collaborative partnerships," Journal of Business Research, Elsevier, vol. 101(C), pages 268-284.
    59. Kumari, Pooja & Shankar, Amit & Behl, Abhishek & Pereira, Vijay & Yahiaoui, Dorra & Laker, Benjamin & Gupta, Brij B. & Arya, Varsha, 2024. "Investigating the barriers towards adoption and implementation of open innovation in healthcare," Technological Forecasting and Social Change, Elsevier, vol. 200(C).
    60. Florence Honoré & Martin Ganco, 2023. "Entrepreneurial teams' acquisition of talent: Evidence from technology manufacturing industries using a two‐sided approach," Strategic Management Journal, Wiley Blackwell, vol. 44(1), pages 141-170, January.
    61. Nawab Khan & Haitao Qu & Jing Qu & ChunMiao Wei & Shihao Wang, 2021. "Does Venture Capital Investment Spur Innovation? A Cross-Countries Analysis," SAGE Open, , vol. 11(1), pages 21582440211, March.
    62. Rothaermel, Frank T. & Deeds, David L., 2006. "Alliance type, alliance experience and alliance management capability in high-technology ventures," Journal of Business Venturing, Elsevier, vol. 21(4), pages 429-460, July.
    63. Eggers, Fabian, 2020. "Masters of disasters? Challenges and opportunities for SMEs in times of crisis," Journal of Business Research, Elsevier, vol. 116(C), pages 199-208.
    64. Gurupdesh Pandher, 2019. "Financier Search and Boundaries of the Angel and VC Markets," Entrepreneurship Theory and Practice, , vol. 43(6), pages 1223-1249, November.
    65. Clarysse, Bart & Moray, Nathalie, 2004. "A process study of entrepreneurial team formation: the case of a research-based spin-off," Journal of Business Venturing, Elsevier, vol. 19(1), pages 55-79, January.
    66. Eric A. Morse & Sally W. Fowler & Thomas B. Lawrence, 2007. "The Impact of Virtual Embeddedness on New Venture Survival: Overcoming the Liabilities of Newness1," Entrepreneurship Theory and Practice, , vol. 31(2), pages 139-159, March.
    67. Liang Chen & Mengmeng Wang & Lin Cui & Sali Li, 2021. "Experience base, strategy‐by‐doing and new product performance," Strategic Management Journal, Wiley Blackwell, vol. 42(7), pages 1379-1398, July.
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