Testing against ordered alternatives for multivariate censored survival data
In clinical trials where the treatment groups correspond to increasing dosages of a substance and the outcome is the possibly right-censored time to a certain event, it is desirable to test for increases or decreases in survival times with increasing dose. Furthermore, it may be of interest to study several endpoints simultaneously. Two asymptotically distribution-free tests are considered: one to test the alternative hypothesis that the survival times are stochastically increasing with increasing dose and another to test the alternative that the survival times are stochastically ordered (either increasing or decreasing) with increasing dose. An important special case concerns the general problem of testing for ordered alternatives with incomplete multivariate (repeated measures) data.
If you experience problems downloading a file, check if you have the proper application to view it first. In case of further problems read the IDEAS help page. Note that these files are not on the IDEAS site. Please be patient as the files may be large.
As the access to this document is restricted, you may want to look for a different version under "Related research" (further below) or search for a different version of it.
Volume (Year): 56 (2002)
Issue (Month): 2 (January)
|Contact details of provider:|| Web page: http://www.elsevier.com/wps/find/journaldescription.cws_home/622892/description#description|
|Order Information:|| Postal: http://www.elsevier.com/wps/find/supportfaq.cws_home/regional|
When requesting a correction, please mention this item's handle: RePEc:eee:stapro:v:56:y:2002:i:2:p:207-216. See general information about how to correct material in RePEc.
For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: (Dana Niculescu)
If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.
If references are entirely missing, you can add them using this form.
If the full references list an item that is present in RePEc, but the system did not link to it, you can help with this form.
If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your profile, as there may be some citations waiting for confirmation.
Please note that corrections may take a couple of weeks to filter through the various RePEc services.