IDEAS home Printed from
   My bibliography  Save this article

Variance in randomized play-the-winner clinical trials


  • Matthews, Peter C.
  • Rosenberger, William F.


We derive the exact variance of the allocation proportions in a clinical trial employing a randomized play-the-winner design. Such a result has application in planning studies.

Suggested Citation

  • Matthews, Peter C. & Rosenberger, William F., 1997. "Variance in randomized play-the-winner clinical trials," Statistics & Probability Letters, Elsevier, vol. 35(3), pages 233-240, October.
  • Handle: RePEc:eee:stapro:v:35:y:1997:i:3:p:233-240

    Download full text from publisher

    File URL:
    Download Restriction: Full text for ScienceDirect subscribers only

    As the access to this document is restricted, you may want to search for a different version of it.

    References listed on IDEAS

    1. Gouet, Raúl, 1989. "A martingale approach to strong convergence in a generalized Pólya-Eggenberger urn model," Statistics & Probability Letters, Elsevier, vol. 8(3), pages 225-228, August.
    2. Smythe, R. T., 1996. "Central limit theorems for urn models," Stochastic Processes and their Applications, Elsevier, vol. 65(1), pages 115-137, December.
    Full references (including those not matched with items on IDEAS)


    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.

    Cited by:

    1. Uttam Bandyopadhyay & Atanu Biswas, 2000. "Some sequential-type conditional tests in clinical trials based on generalized randomized play-the-winner rule," Metron - International Journal of Statistics, Dipartimento di Statistica, Probabilità e Statistiche Applicate - University of Rome, vol. 0(1-2), pages 187-200.


    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:stapro:v:35:y:1997:i:3:p:233-240. See general information about how to correct material in RePEc.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: (Dana Niculescu). General contact details of provider: .

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service hosted by the Research Division of the Federal Reserve Bank of St. Louis . RePEc uses bibliographic data supplied by the respective publishers.