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Optimal designs for comparing population curves in hierarchical models

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  • Liu, Xin
  • Ye, Min
  • Yue, Rong-Xian

Abstract

We construct μp-optimal approximate designs for comparing population curves in hierarchical models with group-specific treatment. Equivalence theorems are given to confirm μp-optimality of designs and the optimal allocation of sample size in each group. An illustrative application to find μ1 and μ∞-optimal designs is presented for the random slope models with two-treatment group assignments.

Suggested Citation

  • Liu, Xin & Ye, Min & Yue, Rong-Xian, 2021. "Optimal designs for comparing population curves in hierarchical models," Statistics & Probability Letters, Elsevier, vol. 178(C).
  • Handle: RePEc:eee:stapro:v:178:y:2021:i:c:s0167715221001541
    DOI: 10.1016/j.spl.2021.109192
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    References listed on IDEAS

    as
    1. Maryna Prus, 2019. "Optimal designs for minimax-criteria in random coefficient regression models," Statistical Papers, Springer, vol. 60(2), pages 465-478, April.
    2. Dette, Holger & Schorning, Kirsten & Konstantinou, Maria, 2017. "Optimal designs for comparing regression models with correlated observations," Computational Statistics & Data Analysis, Elsevier, vol. 113(C), pages 273-286.
    3. Maryna Prus, 2020. "Optimal designs in multiple group random coefficient regression models," TEST: An Official Journal of the Spanish Society of Statistics and Operations Research, Springer;Sociedad de Estadística e Investigación Operativa, vol. 29(1), pages 233-254, March.
    4. W. Liu & F. Bretz & A. J. Hayter & H. P. Wynn, 2009. "Assessing Nonsuperiority, Noninferiority, or Equivalence When Comparing Two Regression Models Over a Restricted Covariate Region," Biometrics, The International Biometric Society, vol. 65(4), pages 1279-1287, December.
    5. Thomas Schmelter, 2007. "The Optimality of Single-group Designs for Certain Mixed Models," Metrika: International Journal for Theoretical and Applied Statistics, Springer, vol. 65(2), pages 183-193, February.
    6. Maryna Prus & Rainer Schwabe, 2016. "Optimal designs for the prediction of individual parameters in hierarchical models," Journal of the Royal Statistical Society Series B, Royal Statistical Society, vol. 78(1), pages 175-191, January.
    7. Prus, Maryna, 2019. "Various optimality criteria for the prediction of individual response curves," Statistics & Probability Letters, Elsevier, vol. 146(C), pages 36-41.
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