Fecal microbiota transplantation as an effective therapeutic alternative

Antibiotic-associated diarrhoea was a common complication of antimicrobial treatment, mainly caused by an imbalance in the gut microbiota. Clostridioides difficile was identified as the most frequent causative agent, capable of triggering pseudomembranous colitis, especially in vulnerable patients. Given the high recurrence rates of conventional treatments, faecal microbiota transplantation was evaluated as an effective therapeutic alternative. This procedure involved transferring faecal material from a healthy donor to an affected recipient, achieving remarkable restoration of intestinal balance, reduced mortality, and significant clinical improvement. In addition to its efficacy, a favourable safety profile and reduced healthcare costs were documented, consolidating it as a key tool in the treatment of recurrent C. difficile infections.