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Maternal Microbiota: changes and consequences during pregnancy. A Narrative Review

Author

Listed:
  • Melany Tello-Silva
  • Noemí Tuanama Shupingahua
  • Maritza Tuesta Pérez
  • Flor María-Vega
  • Noemí Perales
  • Víctor Álvarez-Manrique
  • Liset Z. Sairitupa-Sanchez
  • Mardel Morales-García
  • Wilter C. Morales-García

Abstract

Objective:This study aims to review the changes in microbiota during pregnancy, characterized by natural and associative aspects. Design: A literature review based on a narrative synthesis. Data Sources: The study was conducted using databases such as PubMed, Science Direct, Web of Science (WOS), Scielo, and Google Scholar. Study Selection: Documents were selected and analyzed through an exhaustive literature review, applying specific inclusion and exclusion criteria. Results: For the results analysis, 15 articles were selected, including 3 observational studies, 4 clinical trials, 7 statistical analyses, 2 systematic reviews, and 1 narrative review. The research population consisted of both healthy pregnant women and those with pre-existing conditions. Some studies were conducted in Europe, the United States, Australia, China, and South America. Conclusion: Changes in microbiota during pregnancy influence body mass index (BMI) and are associated with hypertensive disorders, gestational diabetes, the use of prebiotic supplements, and periodontitis. Moreover, microbiota is naturally linked to vaginal function changes, contributes to the infant’s immune system development, and provides beneficial bacteria through breast milk.

Suggested Citation

Handle: RePEc:dbk:sicomu:2025v3a35
DOI: 10.62486/sic2025187
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