Dental health, sports, and quality of life: the impact of periodontal disease on athletic performance

Dysbiotic dental biofilm may increase the risk of periodontal damage and increase proinflammatory mediators such as IL-1β, IL-6, IL-8, C-reactive protein, and TNF-α. Some of these biomarkers are linked to muscle fatigue, the risk of sports injuries, and persistent inflammation in high-intensity exercisers. Studies show that athletes with signs and symptoms of periodontal disease are more likely to suffer recurrent muscle injuries. Inflammatory mediators shared by PD and high-intensity exercise may be linked to an increased risk of fatigue, repeated muscle injuries, and a potential worsening of both PD and muscle function, which subsequently causes plasma creatine kinase (CK) leakage. Studies show that, in the presence of PD, salivary CK concentrations were increased in periodontitis. Other studies show that saliva can be used to detect muscle damage. Therefore, the objective of this work is to investigate the relationship between periodontal disease and sports performance, measurable by salivary biomarkers such as creatine kinase (CK). The increase in the concentration levels of CK present in saliva in periodontal patients