Faecal microbiota transplantation: an emerging solution for recurrent infections

Clostridioides difficile infection was one of the main causes of antibiotic-associated diarrhoea, especially in Latin America, where its incidence increased considerably. Traditionally, it was treated with antibiotics such as metronidazole and vancomycin, although fidaxomicin emerged as a more effective option. However, the high recurrence rates prompted exploration of faecal microbiota transplantation (FMT), which proved more effective in recurrent cases. Although FMT was recognised as a promising therapy, its implementation in Latin America faced barriers such as a lack of protocols, infrastructure, regulation and cultural acceptance. Despite these challenges, scientific evidence supported its progressive incorporation into health systems.