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The neurological impact of post-traumatic stress disorder on the development of degenerative diseases

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  • Deprá, Fabiane Simone
  • Lombisani, Liliana

Abstract

Post-traumatic stress disorder (PTSD) from a neurobiological perspective, beyond its traditional psychological approach. The study analysed how PTSD, by inducing alterations in brain areas such as the hippocampus and prefrontal cortex, may have increased the risk of developing frontotemporal dementia (FTD). The research reviewed identified common mechanisms between the two conditions, such as neuroinflammation and synaptic dysfunction, which suggested a possible causal link. Furthermore, it was considered that chronic stress may not only have acted as a trigger for neurodegenerative diseases, but may also have been aggravated by them. Finally, it was proposed that early identification and management of chronic stress could have contributed to preventing or delaying the onset of FTD.

Suggested Citation

  • Deprá, Fabiane Simone & Lombisani, Liliana, 2024. "The neurological impact of post-traumatic stress disorder on the development of degenerative diseases," SAP Health and Policy, South American Publishing.
    • Handle: RePEc:cwf:shpart:shp2024113
    DOI: 10.56294/shp2024113
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